22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine

C123H119ClF4N30O6 — CID 164994563

About 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine

22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine (PubChem CID 164994563) has the molecular formula C123H119ClF4N30O6 and a molecular weight of 2224.95 g/mol. Its IUPAC name is 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine.

Molecular Properties

• Compound Name: 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine
• PubChem CID: 164994563
• Molecular Formula: C123H119ClF4N30O6
• Molecular Weight: 2224.95 g/mol
• Exact Mass: 2222.96
• IUPAC Name: 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine
• SMILES: CCn1nc(Cl)c2c1-c1cnc(N)c(c1)OC(C)c1cc(C)ccc1-c1nn(C)cc1C2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C3CCC3)noc1Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(cnn1CC(F)(F)F)Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(nn(C(C)C)c1C#N)Cc1ccnn1-2.Cc1ccc2c(c1)COc1cc(cnc1N)-c1c(C#N)nn(C)c1Cc1cc(F)cnc1-2
• InChI: InChI=1S/C26H27N5O2.C25H25N7O.C24H25ClN6O.C24H23F3N6O.C24H19FN6O/c1-14-7-8-19-20(9-14)15(2)32-22-10-17(12-28-26(22)27)23-21(11-18-13-31(3)29-24(18)19)33-30-25(23)16-5-4-6-16;1-14(2)31-22(12-26)24-17-10-23(25(27)28-13-17)33-16(4)19-9-15(3)5-6-21(19)32-18(7-8-29-32)11-20(24)30-31;1-5-31-22-15-10-20(24(26)27-11-15)32-14(3)18-8-13(2)6-7-17(18)21-16(12-30(4)28-21)9-19(22)23(25)29-31;1-13-4-5-18-19(6-13)14(2)34-20-8-16(9-29-23(20)28)22-15(7-17-11-32(3)31-21(17)18)10-30-33(22)12-24(25,26)27;1-13-3-4-18-16(5-13)12-32-21-8-15(10-29-24(21)27)22-19(9-26)30-31(2)20(22)7-14-6-17(25)11-28-23(14)18/h7-10,12-13,15-16H,4-6,11H2,1-3H3,(H2,27,28);5-10,13-14,16H,11H2,1-4H3,(H2,27,28);6-8,10-12,14H,5,9H2,1-4H3,(H2,26,27);4-6,8-11,14H,7,12H2,1-3H3,(H2,28,29);3-6,8,10-11H,7,12H2,1-2H3,(H2,27,29)
• InChIKey: HJBVIXJOQRVSEI-UHFFFAOYSA-N
• XLogP: 23.58
• TPSA: 469.76 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 36
• Rotatable Bonds: 4
• Heavy Atoms: 164
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2224.95
LogP ≤ 5	23.58
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	36

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_OC_no_alk_C(3)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine?

The IUPAC name of 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine (CID 164994563) is 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine.

What is the SMILES notation for 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine?

The canonical SMILES for 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine is CCn1nc(Cl)c2c1-c1cnc(N)c(c1)OC(C)c1cc(C)ccc1-c1nn(C)cc1C2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C3CCC3)noc1Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(cnn1CC(F)(F)F)Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(nn(C(C)C)c1C#N)Cc1ccnn1-2.Cc1ccc2c(c1)COc1cc(cnc1N)-c1c(C#N)nn(C)c1Cc1cc(F)cnc1-2.

What is the InChIKey of 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine?

The InChIKey is HJBVIXJOQRVSEI-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H27N5O2.C25H25N7O.C24H25ClN6O.C24H23F3N6O.C24H19FN6O/c1-14-7-8-19-20(9-14)15(2)32-22-10-17(12-28-26(22)27)23-21(11-18-13-31(3)29-24(18)19)33-30-25(23)16-5-4-6-16;1-14(2)31-22(12-26)24-17-10-23(25(27)28-13-17)33-16(4)19-9-15(3)5-6-21(19)32-18(7-8-29-32)11-20(24)30-31;1-5-31-22-15-10-20(24(26)27-11-15)32-14(3)18-8-13(2)6-7-17(18)21-16(12-30(4)28-21)9-19(22)23(25)29-31;1-13-4-5-18-19(6-13)14(2)34-20-8-16(9-29-23(20)28)22-15(7-17-11-32(3)31-21(17)18)10-30-33(22)12-24(25,26)27;1-13-3-4-18-16(5-13)12-32-21-8-15(10-29-24(21)27)22-19(9-26)30-31(2)20(22)7-14-6-17(25)11-28-23(14)18/h7-10,12-13,15-16H,4-6,11H2,1-3H3,(H2,27,28);5-10,13-14,16H,11H2,1-4H3,(H2,27,28);6-8,10-12,14H,5,9H2,1-4H3,(H2,26,27);4-6,8-11,14H,7,12H2,1-3H3,(H2,28,29);3-6,8,10-11H,7,12H2,1-2H3,(H2,27,29).

What are the key properties of 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine?

22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine has a molecular weight of 2224.95 g/mol, XLogP of 23.58, 4 rotatable bonds, 5 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 22-amino-16,19-dimethyl-4-propan-2-yl-20-oxa-4,5,11,12,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,5,8,10,13(18),14,16,21,23-decaene-3-carbonitrile;23-amino-10-fluoro-5,17-dimethyl-21-oxa-4,5,12,24-tetrazapentacyclo[20.3.1.02,6.08,13.014,19]hexacosa-1(26),2(6),3,8(13),9,11,14(19),15,17,22,24-undecaene-3-carbonitrile;5-chloro-3-ethyl-10,16,19-trimethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine;3-cyclobutyl-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine;10,16,19-trimethyl-3-(2,2,2-trifluoroethyl)-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8,11,13(18),14,16,21,23-decaen-22-amine is sourced from PubChem (CID 164994563), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).