22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine

C121H117ClF2N32O6 — CID 165085673

About 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine

22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine (PubChem CID 165085673) has the molecular formula C121H117ClF2N32O6 and a molecular weight of 2188.93 g/mol. Its IUPAC name is 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine.

Molecular Properties

• Compound Name: 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine
• PubChem CID: 165085673
• Molecular Formula: C121H117ClF2N32O6
• Molecular Weight: 2188.93 g/mol
• Exact Mass: 2186.95
• IUPAC Name: 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine
• SMILES: Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C#N)cnn1Cc1cnn(C)c1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C#N)n[nH]c1Cc1cnn(C)c1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C#N)nn(C)c1Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(CC(F)F)noc1Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(c(C)nn1CC1CC1)Cc1c(Cl)nn(C)c1-2
• InChI: InChI=1S/C27H29ClN6O.C24H23F2N5O2.C24H23N7O.2C23H21N7O/c1-14-5-8-19-21(9-14)16(3)35-23-10-18(12-30-27(23)29)24-20(11-22-25(19)33(4)32-26(22)28)15(2)31-34(24)13-17-6-7-17;1-12-4-5-16-17(6-12)13(2)32-20-7-14(10-28-24(20)27)22-18(9-21(25)26)30-33-19(22)8-15-11-31(3)29-23(15)16;1-13-5-6-17-18(7-13)14(2)32-21-9-15(11-27-24(21)26)22-19(10-25)28-31(4)20(22)8-16-12-30(3)29-23(16)17;1-13-4-5-18-19(6-13)14(2)31-20-7-15(9-26-23(20)25)21-16(8-24)10-28-30(21)12-17-11-27-29(3)22(17)18;1-12-4-5-16-17(6-12)13(2)31-20-8-14(10-26-23(20)25)21-18(28-29-19(21)9-24)7-15-11-27-30(3)22(15)16/h5,8-10,12,16-17H,6-7,11,13H2,1-4H3,(H2,29,30);4-7,10-11,13,21H,8-9H2,1-3H3,(H2,27,28);5-7,9,11-12,14H,8H2,1-4H3,(H2,26,27);4-7,9-11,14H,12H2,1-3H3,(H2,25,26);4-6,8,10-11,13H,7H2,1-3H3,(H2,25,26)(H,28,29)
• InChIKey: VWCZRFVQIHPLCS-UHFFFAOYSA-N
• XLogP: 21.51
• TPSA: 509.34 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 37
• Rotatable Bonds: 4
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2188.93
LogP ≤ 5	21.51
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine?

The IUPAC name of 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine (CID 165085673) is 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine.

What is the SMILES notation for 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine?

The canonical SMILES for 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine is Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C#N)cnn1Cc1cnn(C)c1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C#N)n[nH]c1Cc1cnn(C)c1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(C#N)nn(C)c1Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(CC(F)F)noc1Cc1cn(C)nc1-2.Cc1ccc2c(c1)C(C)Oc1cc(cnc1N)-c1c(c(C)nn1CC1CC1)Cc1c(Cl)nn(C)c1-2.

What is the InChIKey of 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine?

The InChIKey is VWCZRFVQIHPLCS-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H29ClN6O.C24H23F2N5O2.C24H23N7O.2C23H21N7O/c1-14-5-8-19-21(9-14)16(3)35-23-10-18(12-30-27(23)29)24-20(11-22-25(19)33(4)32-26(22)28)15(2)31-34(24)13-17-6-7-17;1-12-4-5-16-17(6-12)13(2)32-20-7-14(10-28-24(20)27)22-18(9-21(25)26)30-33-19(22)8-15-11-31(3)29-23(15)16;1-13-5-6-17-18(7-13)14(2)32-21-9-15(11-27-24(21)26)22-19(10-25)28-31(4)20(22)8-16-12-30(3)29-23(16)17;1-13-4-5-18-19(6-13)14(2)31-20-7-15(9-26-23(20)25)21-16(8-24)10-28-30(21)12-17-11-27-29(3)22(17)18;1-12-4-5-16-17(6-12)13(2)31-20-8-14(10-26-23(20)25)21-18(28-29-19(21)9-24)7-15-11-27-30(3)22(15)16/h5,8-10,12,16-17H,6-7,11,13H2,1-4H3,(H2,29,30);4-7,10-11,13,21H,8-9H2,1-3H3,(H2,27,28);5-7,9,11-12,14H,8H2,1-4H3,(H2,26,27);4-7,9-11,14H,12H2,1-3H3,(H2,25,26);4-6,8,10-11,13H,7H2,1-3H3,(H2,25,26)(H,28,29).

What are the key properties of 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine?

22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine has a molecular weight of 2188.93 g/mol, XLogP of 21.51, 4 rotatable bonds, 6 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 22-amino-5,10,16,19-tetramethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-4,5,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;22-amino-11,16,19-trimethyl-20-oxa-5,6,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2,4,8(12),9,13(18),14,16,21,23-decaene-3-carbonitrile;9-chloro-3-(cyclopropylmethyl)-5,11,16,19-tetramethyl-20-oxa-3,4,10,11,23-pentazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),4,8(12),9,13(18),14,16,21,23-decaen-22-amine;3-(2,2-difluoroethyl)-10,16,19-trimethyl-5,20-dioxa-4,10,11,23-tetrazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(25),2(6),3,8,11,13(18),14,16,21,23-decaen-22-amine is sourced from PubChem (CID 165085673), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).