7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide

C139H156ClF6N45O15 — CID 165029218

IUPAC7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCC(C)(C)CNC(=O)c1cnn2c(N)cc(Nc3cccc4c3OCO4)nc12.CCC(C)(C)CNC(=O)c1cnn2c(NC3CC3)cc(Nc3cccc4c3OCO4)nc12.CNc1cc(Nc2cc(C)cnc2OC)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cc(Cl)ccc2OC(F)(F)F)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccc3c(c2)CCN(C)C3)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cccc(N3CCOCC3)c2)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccccc2OC(F)(F)F)nc2c(C(=O)NC3CC3)cnn12
InChIInChI=1S/C23H28N6O3.C21H25N7O2.C21H25N7O.C20H24N6O3.C18H16ClF3N6O2.C18H17F3N6O2.C18H21N7O2/c1-4-23(2,3)12-24-22(30)15-11-25-29-19(26-14-8-9-14)10-18(28-21(15)29)27-16-6-5-7-17-20(16)32-13-31-17;1-22-19-12-18(24-15-3-2-4-16(11-15)27-7-9-30-10-8-27)26-20-17(13-23-28(19)20)21(29)25-14-5-6-14;1-22-19-10-18(24-16-4-3-14-12-27(2)8-7-13(14)9-16)26-20-17(11-23-28(19)20)21(29)25-15-5-6-15;1-4-20(2,3)10-22-19(27)12-9-23-26-15(21)8-16(25-18(12)26)24-13-6-5-7-14-17(13)29-11-28-14;1-23-15-7-14(26-12-6-9(19)2-5-13(12)30-18(20,21)22)27-16-11(8-24-28(15)16)17(29)25-10-3-4-10;1-22-15-8-14(25-12-4-2-3-5-13(12)29-18(19,20)21)26-16-11(9-23-27(15)16)17(28)24-10-6-7-10;1-10-6-13(18(27-3)20-8-10)23-14-7-15(19-2)25-16(24-14)12(9-21-25)17(26)22-11-4-5-11/h5-7,10-11,14,26H,4,8-9,12-13H2,1-3H3,(H,24,30)(H,27,28);2-4,11-14,22H,5-10H2,1H3,(H,24,26)(H,25,29);3-4,9-11,15,22H,5-8,12H2,1-2H3,(H,24,26)(H,25,29);5-9H,4,10-11,21H2,1-3H3,(H,22,27)(H,24,25);2,5-8,10,23H,3-4H2,1H3,(H,25,29)(H,26,27);2-5,8-10,22H,6-7H2,1H3,(H,24,28)(H,25,26);6-9,11,19H,4-5H2,1-3H3,(H,22,26)(H,23,24)
InChIKeyMJKWYACJVLMDNO-UHFFFAOYSA-N
MW2846.52 g/mol
LogP20.91
Rot. Bonds43

About 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide

7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 165029218) has the molecular formula C139H156ClF6N45O15 and a molecular weight of 2846.52 g/mol. Its IUPAC name is 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID165029218
Molecular FormulaC139H156ClF6N45O15
Molecular Weight2846.52 g/mol
Exact Mass2844.24
IUPAC Name7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCC(C)(C)CNC(=O)c1cnn2c(N)cc(Nc3cccc4c3OCO4)nc12.CCC(C)(C)CNC(=O)c1cnn2c(NC3CC3)cc(Nc3cccc4c3OCO4)nc12.CNc1cc(Nc2cc(C)cnc2OC)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cc(Cl)ccc2OC(F)(F)F)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccc3c(c2)CCN(C)C3)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cccc(N3CCOCC3)c2)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccccc2OC(F)(F)F)nc2c(C(=O)NC3CC3)cnn12
InChIInChI=1S/C23H28N6O3.C21H25N7O2.C21H25N7O.C20H24N6O3.C18H16ClF3N6O2.C18H17F3N6O2.C18H21N7O2/c1-4-23(2,3)12-24-22(30)15-11-25-29-19(26-14-8-9-14)10-18(28-21(15)29)27-16-6-5-7-17-20(16)32-13-31-17;1-22-19-12-18(24-15-3-2-4-16(11-15)27-7-9-30-10-8-27)26-20-17(13-23-28(19)20)21(29)25-14-5-6-14;1-22-19-10-18(24-16-4-3-14-12-27(2)8-7-13(14)9-16)26-20-17(11-23-28(19)20)21(29)25-15-5-6-15;1-4-20(2,3)10-22-19(27)12-9-23-26-15(21)8-16(25-18(12)26)24-13-6-5-7-14-17(13)29-11-28-14;1-23-15-7-14(26-12-6-9(19)2-5-13(12)30-18(20,21)22)27-16-11(8-24-28(15)16)17(29)25-10-3-4-10;1-22-15-8-14(25-12-4-2-3-5-13(12)29-18(19,20)21)26-16-11(9-23-27(15)16)17(28)24-10-6-7-10;1-10-6-13(18(27-3)20-8-10)23-14-7-15(19-2)25-16(24-14)12(9-21-25)17(26)22-11-4-5-11/h5-7,10-11,14,26H,4,8-9,12-13H2,1-3H3,(H,24,30)(H,27,28);2-4,11-14,22H,5-10H2,1H3,(H,24,26)(H,25,29);3-4,9-11,15,22H,5-8,12H2,1-2H3,(H,24,26)(H,25,29);5-9H,4,10-11,21H2,1-3H3,(H,22,27)(H,24,25);2,5-8,10,23H,3-4H2,1H3,(H,25,29)(H,26,27);2-5,8-10,22H,6-7H2,1H3,(H,24,28)(H,25,26);6-9,11,19H,4-5H2,1-3H3,(H,22,26)(H,23,24)
InChIKeyMJKWYACJVLMDNO-UHFFFAOYSA-N
XLogP20.91
TPSA690.65 Ų
H-Bond Donors21
H-Bond Acceptors53
Rotatable Bonds43
Heavy Atoms206
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002846.52
LogP ≤ 520.91
H-Bond Donors ≤ 521
H-Bond Acceptors ≤ 1053

Analyze 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

N-[5-[(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-5-(1-methylpyrrolo[2,3-b]pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-5-[1-(oxolan-3-yl)pyrrolo[2,3-b]pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-5-[[7-(trifluoromethyl)-2,3-dihydro-1,4-benzodioxin-5-yl]amino]pyrazolo[1,5-a]pyrimidin-3-yl]propanamide
CID 161759002
5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[(5-chloro-1,3-benzodioxol-4-yl)amino]-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[3-(4-methylpiperazin-1-yl)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methylpyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[(2,2-difluoro-1,3-benzodioxol-4-yl)amino]-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-ethyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165024655
5-[[C-(2-aminoethenyl)-N-(2,2,2-trifluoroethyl)carbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-(2-hydroxyethyl)pyrazol-3-yl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)-N-(2-methylcyclopropyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone;5-(3,5-difluoro-2-methoxyanilino)-N-methyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-7-(methylamino)-N-(oxolan-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-dimethylanilino)-7-(ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone
CID 165032658
N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,3-dihydroxy-2-methylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-7-(methylamino)-N-(oxolan-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165051494
5-[[C-(2-aminoethenyl)-N-(2-hydroxyethyl)carbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[[C-(2-aminoethenyl)-N-(2,2,2-trifluoroethyl)carbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)-N-(2-methylcyclopropyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone;5-(3,5-difluoro-2-methoxyanilino)-N-methyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(3,3-dimethylcyclobutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-dimethylanilino)-7-(ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone
CID 165068281
7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165092275
5-[[C-(2-aminoethenyl)-N-methylcarbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[(5-chloro-1,3-benzodioxol-4-yl)amino]-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[3-(4-methylpiperazin-1-yl)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[(2,2-difluoro-1,3-benzodioxol-4-yl)amino]-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-ethyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165098538
N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165107816
N-[5-(1,3-benzodioxol-4-ylamino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[5-[(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-cyclopropylacetamide;N-[7-(methylamino)-5-[1-(oxetan-3-yl)pyrrolo[2,3-b]pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide
CID 161712753
CID 165032439
CID 165032439
CID 165075203
CID 165075203

Frequently Asked Questions

What is the IUPAC name of 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 165029218) is 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide is CCC(C)(C)CNC(=O)c1cnn2c(N)cc(Nc3cccc4c3OCO4)nc12.CCC(C)(C)CNC(=O)c1cnn2c(NC3CC3)cc(Nc3cccc4c3OCO4)nc12.CNc1cc(Nc2cc(C)cnc2OC)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cc(Cl)ccc2OC(F)(F)F)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccc3c(c2)CCN(C)C3)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cccc(N3CCOCC3)c2)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccccc2OC(F)(F)F)nc2c(C(=O)NC3CC3)cnn12.
What is the InChIKey of 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is MJKWYACJVLMDNO-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H28N6O3.C21H25N7O2.C21H25N7O.C20H24N6O3.C18H16ClF3N6O2.C18H17F3N6O2.C18H21N7O2/c1-4-23(2,3)12-24-22(30)15-11-25-29-19(26-14-8-9-14)10-18(28-21(15)29)27-16-6-5-7-17-20(16)32-13-31-17;1-22-19-12-18(24-15-3-2-4-16(11-15)27-7-9-30-10-8-27)26-20-17(13-23-28(19)20)21(29)25-14-5-6-14;1-22-19-10-18(24-16-4-3-14-12-27(2)8-7-13(14)9-16)26-20-17(11-23-28(19)20)21(29)25-15-5-6-15;1-4-20(2,3)10-22-19(27)12-9-23-26-15(21)8-16(25-18(12)26)24-13-6-5-7-14-17(13)29-11-28-14;1-23-15-7-14(26-12-6-9(19)2-5-13(12)30-18(20,21)22)27-16-11(8-24-28(15)16)17(29)25-10-3-4-10;1-22-15-8-14(25-12-4-2-3-5-13(12)29-18(19,20)21)26-16-11(9-23-27(15)16)17(28)24-10-6-7-10;1-10-6-13(18(27-3)20-8-10)23-14-7-15(19-2)25-16(24-14)12(9-21-25)17(26)22-11-4-5-11/h5-7,10-11,14,26H,4,8-9,12-13H2,1-3H3,(H,24,30)(H,27,28);2-4,11-14,22H,5-10H2,1H3,(H,24,26)(H,25,29);3-4,9-11,15,22H,5-8,12H2,1-2H3,(H,24,26)(H,25,29);5-9H,4,10-11,21H2,1-3H3,(H,22,27)(H,24,25);2,5-8,10,23H,3-4H2,1H3,(H,25,29)(H,26,27);2-5,8-10,22H,6-7H2,1H3,(H,24,28)(H,25,26);6-9,11,19H,4-5H2,1-3H3,(H,22,26)(H,23,24).
What are the key properties of 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2846.52 g/mol, XLogP of 20.91, 43 rotatable bonds, 21 hydrogen bond donors, and 53 hydrogen bond acceptors.
Where does this data come from?
All data for 7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 165029218), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).