N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C141H165F3N52O17 — CID 165107816

IUPACN-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCC(C)(C)CNC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(OC)nn4)c3=O)nc12.CCC(C)(O)CNC(=O)c1cnn2c(NC)cc(Nc3cccc4c3OCCO4)nc12.CCNC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(OC)nn4)c3=O)nc12.CCn1ccc(Nc2cc(NC)n3ncc(C(=O)NC4CC4)c3n2)n1.CNc1cc(Nc2cc(C(F)(F)F)cnc2OC)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccc3c(c2)CN(C)CC3)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cccc3c2OCCO3)nc2c(C(=O)NCC(C)(C)C)cnn12
InChIInChI=1S/C24H29N9O3.C21H25N7O.C21H26N6O4.C21H26N6O3.C20H21N9O3.C18H18F3N7O2.C16H20N8O/c1-6-24(2,3)14-26-22(34)15-13-27-33-19(25-4)12-17(29-21(15)33)28-16-8-7-11-32(23(16)35)18-9-10-20(36-5)31-30-18;1-22-19-10-18(24-16-4-3-13-7-8-27(2)12-14(13)9-16)26-20-17(11-23-28(19)20)21(29)25-15-5-6-15;1-4-21(2,29)12-23-20(28)13-11-24-27-17(22-3)10-16(26-19(13)27)25-14-6-5-7-15-18(14)31-9-8-30-15;1-21(2,3)12-23-20(28)13-11-24-27-17(22-4)10-16(26-19(13)27)25-14-6-5-7-15-18(14)30-9-8-29-15;1-4-22-19(30)12-11-23-29-16(21-2)10-14(25-18(12)29)24-13-6-5-9-28(20(13)31)15-7-8-17(32-3)27-26-15;1-22-14-6-13(26-12-5-9(18(19,20)21)7-23-17(12)30-2)27-15-11(8-24-28(14)15)16(29)25-10-3-4-10;1-3-23-7-6-12(22-23)20-13-8-14(17-2)24-15(21-13)11(9-18-24)16(25)19-10-4-5-10/h7-13,25H,6,14H2,1-5H3,(H,26,34)(H,28,29);3-4,9-11,15,22H,5-8,12H2,1-2H3,(H,24,26)(H,25,29);5-7,10-11,22,29H,4,8-9,12H2,1-3H3,(H,23,28)(H,25,26);5-7,10-11,22H,8-9,12H2,1-4H3,(H,23,28)(H,25,26);5-11,21H,4H2,1-3H3,(H,22,30)(H,24,25);5-8,10,22H,3-4H2,1-2H3,(H,25,29)(H,26,27);6-10,17H,3-5H2,1-2H3,(H,19,25)(H,20,21,22)
InChIKeyZLBOVIOCRKLLIQ-UHFFFAOYSA-N
MW2917.21 g/mol
LogP15.93
Rot. Bonds45

About N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide

N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 165107816) has the molecular formula C141H165F3N52O17 and a molecular weight of 2917.21 g/mol. Its IUPAC name is N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound NameN-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID165107816
Molecular FormulaC141H165F3N52O17
Molecular Weight2917.21 g/mol
Exact Mass2915.36
IUPAC NameN-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCCC(C)(C)CNC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(OC)nn4)c3=O)nc12.CCC(C)(O)CNC(=O)c1cnn2c(NC)cc(Nc3cccc4c3OCCO4)nc12.CCNC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(OC)nn4)c3=O)nc12.CCn1ccc(Nc2cc(NC)n3ncc(C(=O)NC4CC4)c3n2)n1.CNc1cc(Nc2cc(C(F)(F)F)cnc2OC)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccc3c(c2)CN(C)CC3)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cccc3c2OCCO3)nc2c(C(=O)NCC(C)(C)C)cnn12
InChIInChI=1S/C24H29N9O3.C21H25N7O.C21H26N6O4.C21H26N6O3.C20H21N9O3.C18H18F3N7O2.C16H20N8O/c1-6-24(2,3)14-26-22(34)15-13-27-33-19(25-4)12-17(29-21(15)33)28-16-8-7-11-32(23(16)35)18-9-10-20(36-5)31-30-18;1-22-19-10-18(24-16-4-3-13-7-8-27(2)12-14(13)9-16)26-20-17(11-23-28(19)20)21(29)25-15-5-6-15;1-4-21(2,29)12-23-20(28)13-11-24-27-17(22-3)10-16(26-19(13)27)25-14-6-5-7-15-18(14)31-9-8-30-15;1-21(2,3)12-23-20(28)13-11-24-27-17(22-4)10-16(26-19(13)27)25-14-6-5-7-15-18(14)30-9-8-29-15;1-4-22-19(30)12-11-23-29-16(21-2)10-14(25-18(12)29)24-13-6-5-9-28(20(13)31)15-7-8-17(32-3)27-26-15;1-22-14-6-13(26-12-5-9(18(19,20)21)7-23-17(12)30-2)27-15-11(8-24-28(14)15)16(29)25-10-3-4-10;1-3-23-7-6-12(22-23)20-13-8-14(17-2)24-15(21-13)11(9-18-24)16(25)19-10-4-5-10/h7-13,25H,6,14H2,1-5H3,(H,26,34)(H,28,29);3-4,9-11,15,22H,5-8,12H2,1-2H3,(H,24,26)(H,25,29);5-7,10-11,22,29H,4,8-9,12H2,1-3H3,(H,23,28)(H,25,26);5-7,10-11,22H,8-9,12H2,1-4H3,(H,23,28)(H,25,26);5-11,21H,4H2,1-3H3,(H,22,30)(H,24,25);5-8,10,22H,3-4H2,1-2H3,(H,25,29)(H,26,27);6-10,17H,3-5H2,1-2H3,(H,19,25)(H,20,21,22)
InChIKeyZLBOVIOCRKLLIQ-UHFFFAOYSA-N
XLogP15.93
TPSA797.80 Ų
H-Bond Donors22
H-Bond Acceptors62
Rotatable Bonds45
Heavy Atoms213
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002917.21
LogP ≤ 515.93
H-Bond Donors ≤ 522
H-Bond Acceptors ≤ 1062

Analyze N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[5-(3,4-dihydro-2H-1,5-benzodioxepin-6-ylamino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-3-(propanoylamino)pyrazolo[1,5-a]pyrimidin-5-yl]benzamide;N-[7-(methylamino)-5-(quinoxalin-5-ylamino)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-5-(5,6,7,8-tetrahydronaphthalen-1-ylamino)pyrazolo[1,5-a]pyrimidin-3-yl]propanamide;N-[7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidin-3-yl]propanamide
CID 157184933
N-[(2R)-2-(hydroxymethyl)-2-methyl-6-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]piperidin-1-yl]-3H-1-benzofuran-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(2S)-2-(hydroxymethyl)-2-methyl-6-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]piperidin-1-yl]-3H-1-benzofuran-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(2R)-2-(hydroxymethyl)-2-methyl-6-[4-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]piperidin-1-yl]-3H-1-benzofuran-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(2S)-2-(hydroxymethyl)-2-methyl-6-[4-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]piperidin-1-yl]-3H-1-benzofuran-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 161172541
7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[2-(trifluoromethoxy)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165029218
5-[[C-(2-aminoethenyl)-N-(2,2,2-trifluoroethyl)carbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-(2-hydroxyethyl)pyrazol-3-yl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)-N-(2-methylcyclopropyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone;5-(3,5-difluoro-2-methoxyanilino)-N-methyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-7-(methylamino)-N-(oxolan-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-dimethylanilino)-7-(ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone
CID 165032658
N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,3-dihydroxy-2-methylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-7-(methylamino)-N-(oxolan-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165051494
5-[[C-(2-aminoethenyl)-N-(2-hydroxyethyl)carbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[[C-(2-aminoethenyl)-N-(2,2,2-trifluoroethyl)carbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)-N-(2-methylcyclopropyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-difluoro-2-methoxyanilino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone;5-(3,5-difluoro-2-methoxyanilino)-N-methyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(3,3-dimethylcyclobutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[5-(3,5-dimethylanilino)-7-(ethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]ethanone
CID 165068281
7-amino-5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-7-(cyclopropylamino)-N-(2,2-dimethylbutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[5-chloro-2-(trifluoromethoxy)anilino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[(2-methoxy-5-methyl-3-pyridinyl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-(3-morpholin-4-ylanilino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165092275
5-[[C-(2-aminoethenyl)-N-methylcarbonimidoyl]amino]-N-cyclopropyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(1,3-benzodioxol-4-ylamino)-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[(5-chloro-1,3-benzodioxol-4-yl)amino]-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[1-(2-methoxyethyl)pyrazol-4-yl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[3-(4-methylpiperazin-1-yl)anilino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-[(2,2-difluoro-1,3-benzodioxol-4-yl)amino]-N-(2,2-dimethylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-ethyl-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 165098538
N-cyclobutyl-5-[[1-[2-[[7-fluoro-5-[[3-[(3-hydroxy-2,2-dimethylpropyl)carbamoyl]-7-(methylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]pyrimidin-4-yl]-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 167050340
CID 167687895
CID 167687895
N-[3-[6-(difluoromethoxy)-3,4-dihydro-2H-1,4-benzoxazin-7-yl]-1-(1-methyl-2-oxopyrrolidin-3-yl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[6-(difluoromethoxy)-3,4-dihydro-2H-1,4-benzoxazin-7-yl]-1-[(3S)-1-methyl-2-oxopyrrolidin-3-yl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-[6-(difluoromethoxy)-3,4-dihydro-2H-1,4-benzoxazin-7-yl]-1-[(3R)-1-methyl-2-oxopyrrolidin-3-yl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157385116
N-[5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(1S,2S)-2-methylcyclopropyl]acetamide;N-[5-[(7-fluoro-2,3-dihydro-1,4-benzodioxin-5-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(1R,2R)-2-methylcyclopropyl]acetamide;N-[5-[(7-fluoro-2,3-dihydro-1,4-benzodioxin-5-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(1R,2S)-2-methylcyclopropyl]acetamide;N-[5-[(7-fluoro-2,3-dihydro-1,4-benzodioxin-5-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylcyclopropyl)acetamide;N-[7-(methylamino)-5-(quinolin-8-ylamino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(1S,2S)-2-methylcyclopropyl]acetamide;N-[7-(methylamino)-5-(2,3,5,6-tetrafluoroanilino)pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(1S,2S)-2-methylcyclopropyl]acetamide
CID 157457847

Frequently Asked Questions

What is the IUPAC name of N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 165107816) is N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide is CCC(C)(C)CNC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(OC)nn4)c3=O)nc12.CCC(C)(O)CNC(=O)c1cnn2c(NC)cc(Nc3cccc4c3OCCO4)nc12.CCNC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(OC)nn4)c3=O)nc12.CCn1ccc(Nc2cc(NC)n3ncc(C(=O)NC4CC4)c3n2)n1.CNc1cc(Nc2cc(C(F)(F)F)cnc2OC)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2ccc3c(c2)CN(C)CC3)nc2c(C(=O)NC3CC3)cnn12.CNc1cc(Nc2cccc3c2OCCO3)nc2c(C(=O)NCC(C)(C)C)cnn12.
What is the InChIKey of N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is ZLBOVIOCRKLLIQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H29N9O3.C21H25N7O.C21H26N6O4.C21H26N6O3.C20H21N9O3.C18H18F3N7O2.C16H20N8O/c1-6-24(2,3)14-26-22(34)15-13-27-33-19(25-4)12-17(29-21(15)33)28-16-8-7-11-32(23(16)35)18-9-10-20(36-5)31-30-18;1-22-19-10-18(24-16-4-3-13-7-8-27(2)12-14(13)9-16)26-20-17(11-23-28(19)20)21(29)25-15-5-6-15;1-4-21(2,29)12-23-20(28)13-11-24-27-17(22-3)10-16(26-19(13)27)25-14-6-5-7-15-18(14)31-9-8-30-15;1-21(2,3)12-23-20(28)13-11-24-27-17(22-4)10-16(26-19(13)27)25-14-6-5-7-15-18(14)30-9-8-29-15;1-4-22-19(30)12-11-23-29-16(21-2)10-14(25-18(12)29)24-13-6-5-9-28(20(13)31)15-7-8-17(32-3)27-26-15;1-22-14-6-13(26-12-5-9(18(19,20)21)7-23-17(12)30-2)27-15-11(8-24-28(14)15)16(29)25-10-3-4-10;1-3-23-7-6-12(22-23)20-13-8-14(17-2)24-15(21-13)11(9-18-24)16(25)19-10-4-5-10/h7-13,25H,6,14H2,1-5H3,(H,26,34)(H,28,29);3-4,9-11,15,22H,5-8,12H2,1-2H3,(H,24,26)(H,25,29);5-7,10-11,22,29H,4,8-9,12H2,1-3H3,(H,23,28)(H,25,26);5-7,10-11,22H,8-9,12H2,1-4H3,(H,23,28)(H,25,26);5-11,21H,4H2,1-3H3,(H,22,30)(H,24,25);5-8,10,22H,3-4H2,1-2H3,(H,25,29)(H,26,27);6-10,17H,3-5H2,1-2H3,(H,19,25)(H,20,21,22).
What are the key properties of N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2917.21 g/mol, XLogP of 15.93, 45 rotatable bonds, 22 hydrogen bond donors, and 62 hydrogen bond acceptors.
Where does this data come from?
All data for N-cyclopropyl-5-[(1-ethylpyrazol-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-5-[[2-methoxy-5-(trifluoromethyl)-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-cyclopropyl-7-(methylamino)-5-[(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2,2-dimethylpropyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;5-(2,3-dihydro-1,4-benzodioxin-5-ylamino)-N-(2-hydroxy-2-methylbutyl)-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(2,2-dimethylbutyl)-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-ethyl-5-[[1-(6-methoxypyridazin-3-yl)-2-oxo-3-pyridinyl]amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 165107816), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).