1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

C128H132Cl6N34O2S5 — CID 165091057

About 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine

1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (PubChem CID 165091057) has the molecular formula C128H132Cl6N34O2S5 and a molecular weight of 2551.75 g/mol. Its IUPAC name is 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

Molecular Properties

• Compound Name: 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• PubChem CID: 165091057
• Molecular Formula: C128H132Cl6N34O2S5
• Molecular Weight: 2551.75 g/mol
• Exact Mass: 2546.80
• IUPAC Name: 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
• SMILES: Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2c(CO)cnc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1ccnc(CC2CC2)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1ccnc(Cl)c1Cl.Cc1nc(N2CCC3(CC2)Oc2ccccc2C3N)n2ccnc2c1Sc1ccnc(N)c1Cl.Nc1nccc(Sc2c(N)nc(N3CCC4(CC3)Cc3ccccc3C4N)n3ccnc23)c1Cl
• InChI: InChI=1S/C29H31ClN6S.C26H28ClN7OS.C25H24Cl2N6S.C24H25ClN8S.C24H24ClN7OS/c1-18-25(37-23-8-11-32-22(24(23)30)16-19-6-7-19)27-33-12-15-36(27)28(34-18)35-13-9-29(10-14-35)17-20-4-2-3-5-21(20)26(29)31;1-15-21(36-19-6-9-30-23(29)20(19)27)24-31-13-17(14-35)34(24)25(32-15)33-10-7-26(8-11-33)12-16-4-2-3-5-18(16)22(26)28;1-15-20(34-18-6-9-29-22(27)19(18)26)23-30-10-13-33(23)24(31-15)32-11-7-25(8-12-32)14-16-4-2-3-5-17(16)21(25)28;25-17-16(5-8-29-20(17)27)34-18-21(28)31-23(33-12-9-30-22(18)33)32-10-6-24(7-11-32)13-14-3-1-2-4-15(14)19(24)26;1-14-19(34-17-6-9-28-21(27)18(17)25)22-29-10-13-32(22)23(30-14)31-11-7-24(8-12-31)20(26)15-4-2-3-5-16(15)33-24/h2-5,8,11-12,15,19,26H,6-7,9-10,13-14,16-17,31H2,1H3;2-6,9,13,22,35H,7-8,10-12,14,28H2,1H3,(H2,29,30);2-6,9-10,13,21H,7-8,11-12,14,28H2,1H3;1-5,8-9,12,19H,6-7,10-11,13,26,28H2,(H2,27,29);2-6,9-10,13,20H,7-8,11-12,26H2,1H3,(H2,27,28)
• InChIKey: WSDWJTPCFNBBGY-UHFFFAOYSA-N
• XLogP: 24.11
• TPSA: 495.24 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 41
• Rotatable Bonds: 18
• Heavy Atoms: 175
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2551.75
LogP ≤ 5	24.11
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	41

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The IUPAC name of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine (CID 165091057) is 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine.

What is the SMILES notation for 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The canonical SMILES for 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2c(CO)cnc2c1Sc1ccnc(N)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1ccnc(CC2CC2)c1Cl.Cc1nc(N2CCC3(CC2)Cc2ccccc2C3N)n2ccnc2c1Sc1ccnc(Cl)c1Cl.Cc1nc(N2CCC3(CC2)Oc2ccccc2C3N)n2ccnc2c1Sc1ccnc(N)c1Cl.Nc1nccc(Sc2c(N)nc(N3CCC4(CC3)Cc3ccccc3C4N)n3ccnc23)c1Cl.

What is the InChIKey of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

The InChIKey is WSDWJTPCFNBBGY-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H31ClN6S.C26H28ClN7OS.C25H24Cl2N6S.C24H25ClN8S.C24H24ClN7OS/c1-18-25(37-23-8-11-32-22(24(23)30)16-19-6-7-19)27-33-12-15-36(27)28(34-18)35-13-9-29(10-14-35)17-20-4-2-3-5-21(20)26(29)31;1-15-21(36-19-6-9-30-23(29)20(19)27)24-31-13-17(14-35)34(24)25(32-15)33-10-7-26(8-11-33)12-16-4-2-3-5-18(16)22(26)28;1-15-20(34-18-6-9-29-22(27)19(18)26)23-30-10-13-33(23)24(31-15)32-11-7-25(8-12-32)14-16-4-2-3-5-17(16)21(25)28;25-17-16(5-8-29-20(17)27)34-18-21(28)31-23(33-12-9-30-22(18)33)32-10-6-24(7-11-32)13-14-3-1-2-4-15(14)19(24)26;1-14-19(34-17-6-9-28-21(27)18(17)25)22-29-10-13-32(22)23(30-14)31-11-7-24(8-12-31)20(26)15-4-2-3-5-16(15)33-24/h2-5,8,11-12,15,19,26H,6-7,9-10,13-14,16-17,31H2,1H3;2-6,9,13,22,35H,7-8,10-12,14,28H2,1H3,(H2,29,30);2-6,9-10,13,21H,7-8,11-12,14,28H2,1H3;1-5,8-9,12,19H,6-7,10-11,13,26,28H2,(H2,27,29);2-6,9-10,13,20H,7-8,11-12,26H2,1H3,(H2,27,28).

What are the key properties of 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine?

1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine has a molecular weight of 2551.75 g/mol, XLogP of 24.11, 18 rotatable bonds, 10 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 1'-[7-amino-8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]imidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-5-(1-aminospiro[1,3-dihydroindene-2,4'-piperidine]-1'-yl)-7-methylimidazo[1,2-c]pyrimidin-3-yl]methanol;1'-[8-[(2-amino-3-chloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[3H-1-benzofuran-2,4'-piperidine]-3-amine;1'-[8-[[3-chloro-2-(cyclopropylmethyl)-4-pyridinyl]sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine;1'-[8-[(2,3-dichloro-4-pyridinyl)sulfanyl]-7-methylimidazo[1,2-c]pyrimidin-5-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine is sourced from PubChem (CID 165091057), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).