N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide

C11H13F3N4O — CID 167035122

IUPACN-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
SMILESO=C(Nc1cncc(C(F)(F)F)n1)C1CCCCN1
InChIInChI=1S/C11H13F3N4O/c12-11(13,14)8-5-15-6-9(17-8)18-10(19)7-3-1-2-4-16-7/h5-7,16H,1-4H2,(H,17,18,19)
InChIKeyVISLSPSGLGEFOJ-UHFFFAOYSA-N
MW274.25 g/mol
LogP1.58
Rot. Bonds2

About N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide

N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide (PubChem CID 167035122) has the molecular formula C11H13F3N4O and a molecular weight of 274.25 g/mol. Its IUPAC name is N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide.

Molecular Properties

Compound NameN-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
PubChem CID167035122
Molecular FormulaC11H13F3N4O
Molecular Weight274.25 g/mol
Exact Mass274.10
IUPAC NameN-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide
SMILESO=C(Nc1cncc(C(F)(F)F)n1)C1CCCCN1
InChIInChI=1S/C11H13F3N4O/c12-11(13,14)8-5-15-6-9(17-8)18-10(19)7-3-1-2-4-16-7/h5-7,16H,1-4H2,(H,17,18,19)
InChIKeyVISLSPSGLGEFOJ-UHFFFAOYSA-N
XLogP1.58
TPSA66.91 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500274.25
LogP ≤ 51.58
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

(3S)-3-[(3,6-dimethylpyrazin-2-yl)amino]azepan-2-one
CID 40506874
N-[(4,4-difluoropiperidin-2-yl)methyl]-5-(trifluoromethyl)pyrazin-2-amine
CID 89782560
(2S,3R)-2-methyl-3-[[5-(trifluoromethyl)pyrazin-2-yl]amino]piperidine-1-carbaldehyde
CID 90405043
N-((2S,3R)-2-methylpiperidin-3-yl)-5-(trifluoromethyl)pyrazin-2-amine
CID 90405811
N-[5-(trifluoromethyl)pyrazin-2-yl]propanamide
CID 121359350
(2S,4R)-4-fluoro-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide;hydrochloride
CID 126643496
(2S,4R)-4-fluoro-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide
CID 126643497
N-piperidin-3-yl-5-(trifluoromethyl)pyrazin-2-amine
CID 134503531
(2S,4R)-N-chloro-4-fluoro-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide
CID 140318889
(2S,3R)-2-methyl-3-[[5-(trifluoromethyl)pyrazin-2-yl]amino]piperidine-1-carboxylic acid
CID 141419434
ethane;4-methyl-N-[6-(trifluoromethyl)pyrazin-2-yl]pyrrolidine-2-carboxamide
CID 156837542
3-(trifluoromethyl)pyrazin-2-amine;N-[3-(trifluoromethyl)pyrazin-2-yl]acetamide
CID 162082127

Frequently Asked Questions

What is the IUPAC name of N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
The IUPAC name of N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide (CID 167035122) is N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide.
What is the SMILES notation for N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
The canonical SMILES for N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide is O=C(Nc1cncc(C(F)(F)F)n1)C1CCCCN1.
What is the InChIKey of N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
The InChIKey is VISLSPSGLGEFOJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H13F3N4O/c12-11(13,14)8-5-15-6-9(17-8)18-10(19)7-3-1-2-4-16-7/h5-7,16H,1-4H2,(H,17,18,19).
What are the key properties of N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide?
N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide has a molecular weight of 274.25 g/mol, XLogP of 1.58, 2 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-(trifluoromethyl)pyrazin-2-yl]piperidine-2-carboxamide is sourced from PubChem (CID 167035122), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).