2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide

C100H74F16N26O11 — CID 167537638

About 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide

2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide (PubChem CID 167537638) has the molecular formula C100H74F16N26O11 and a molecular weight of 2119.83 g/mol. Its IUPAC name is 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide.

Molecular Properties

• Compound Name: 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide
• PubChem CID: 167537638
• Molecular Formula: C100H74F16N26O11
• Molecular Weight: 2119.83 g/mol
• Exact Mass: 2118.58
• IUPAC Name: 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide
• SMILES: Cc1ccc(NC(=O)COc2ccc(-c3cnc4ccccn34)cn2)cc1C(F)(F)F.Cc1ccc(NC(=O)COc2ccc(-c3cnc4cnccn34)cn2)cc1C(F)(F)F.Cc1cnc(NC(=O)COc2ccc(-c3cnc4cnccn34)cn2)cc1C(F)(F)F.Cn1nc(NC(=O)COc2ccc(-c3cnc4ccccn34)c(F)n2)cc1C(F)(F)F.O=C(COc1ccc(-c2cnc3ccccn23)cn1)Nc1cc(C(F)(F)F)on1
• InChI: InChI=1S/C22H17F3N4O2.C21H16F3N5O2.C20H15F3N6O2.C19H14F4N6O2.C18H12F3N5O3/c1-14-5-7-16(10-17(14)22(23,24)25)28-20(30)13-31-21-8-6-15(11-27-21)18-12-26-19-4-2-3-9-29(18)19;1-13-2-4-15(8-16(13)21(22,23)24)28-19(30)12-31-20-5-3-14(9-27-20)17-10-26-18-11-25-6-7-29(17)18;1-12-7-25-16(6-14(12)20(21,22)23)28-18(30)11-31-19-3-2-13(8-27-19)15-9-26-17-10-24-4-5-29(15)17;1-28-13(19(21,22)23)8-14(27-28)25-16(30)10-31-17-6-5-11(18(20)26-17)12-9-24-15-4-2-3-7-29(12)15;19-18(20,21)13-7-14(25-29-13)24-16(27)10-28-17-5-4-11(8-23-17)12-9-22-15-3-1-2-6-26(12)15/h2-12H,13H2,1H3,(H,28,30);2-11H,12H2,1H3,(H,28,30);2-10H,11H2,1H3,(H,25,28,30);2-9H,10H2,1H3,(H,25,27,30);1-9H,10H2,(H,24,25,27)
• InChIKey: ATGDFUJOVWMPCV-UHFFFAOYSA-N
• XLogP: 19.13
• TPSA: 425.12 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 32
• Rotatable Bonds: 25
• Heavy Atoms: 153
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2119.83
LogP ≤ 5	19.13
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	32

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide?

The IUPAC name of 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide (CID 167537638) is 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide.

What is the SMILES notation for 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide?

The canonical SMILES for 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide is Cc1ccc(NC(=O)COc2ccc(-c3cnc4ccccn34)cn2)cc1C(F)(F)F.Cc1ccc(NC(=O)COc2ccc(-c3cnc4cnccn34)cn2)cc1C(F)(F)F.Cc1cnc(NC(=O)COc2ccc(-c3cnc4cnccn34)cn2)cc1C(F)(F)F.Cn1nc(NC(=O)COc2ccc(-c3cnc4ccccn34)c(F)n2)cc1C(F)(F)F.O=C(COc1ccc(-c2cnc3ccccn23)cn1)Nc1cc(C(F)(F)F)on1.

What is the InChIKey of 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide?

The InChIKey is ATGDFUJOVWMPCV-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H17F3N4O2.C21H16F3N5O2.C20H15F3N6O2.C19H14F4N6O2.C18H12F3N5O3/c1-14-5-7-16(10-17(14)22(23,24)25)28-20(30)13-31-21-8-6-15(11-27-21)18-12-26-19-4-2-3-9-29(18)19;1-13-2-4-15(8-16(13)21(22,23)24)28-19(30)12-31-20-5-3-14(9-27-20)17-10-26-18-11-25-6-7-29(17)18;1-12-7-25-16(6-14(12)20(21,22)23)28-18(30)11-31-19-3-2-13(8-27-19)15-9-26-17-10-24-4-5-29(15)17;1-28-13(19(21,22)23)8-14(27-28)25-16(30)10-31-17-6-5-11(18(20)26-17)12-9-24-15-4-2-3-7-29(12)15;19-18(20,21)13-7-14(25-29-13)24-16(27)10-28-17-5-4-11(8-23-17)12-9-22-15-3-1-2-6-26(12)15/h2-12H,13H2,1H3,(H,28,30);2-11H,12H2,1H3,(H,28,30);2-10H,11H2,1H3,(H,25,28,30);2-9H,10H2,1H3,(H,25,27,30);1-9H,10H2,(H,24,25,27).

What are the key properties of 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide?

2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide has a molecular weight of 2119.83 g/mol, XLogP of 19.13, 25 rotatable bonds, 5 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[(6-fluoro-5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyrazin-3-yl-2-pyridinyl)oxy]-N-[5-methyl-4-(trifluoromethyl)-2-pyridinyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[4-methyl-3-(trifluoromethyl)phenyl]acetamide;2-[(5-imidazo[1,2-a]pyridin-3-yl-2-pyridinyl)oxy]-N-[5-(trifluoromethyl)-1,2-oxazol-3-yl]acetamide is sourced from PubChem (CID 167537638), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).