2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C104H112F15N35O11 — CID 159905012

IUPAC2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCN(C)C1CCC(COc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)CC1.CN(C)C1CCC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)CC1.CN(C)Cc1ccc(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)cc1.COCCN1CCCC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OC1CCNCC1
InChIInChI=1S/C22H26F3N7O2.C22H20F3N7O2.C21H24F3N7O3.C21H24F3N7O2.C18H18F3N7O2/c1-31(2)14-5-3-13(4-6-14)12-34-16-7-9-27-11-15(16)28-21(33)18-19(26)30-32-10-8-17(22(23,24)25)29-20(18)32;1-31(2)12-13-3-5-14(6-4-13)34-16-7-9-27-11-15(16)28-21(33)18-19(26)30-32-10-8-17(22(23,24)25)29-20(18)32;1-33-10-9-30-7-2-3-13(12-30)34-15-4-6-26-11-14(15)27-20(32)17-18(25)29-31-8-5-16(21(22,23)24)28-19(17)31;1-30(2)12-3-5-13(6-4-12)33-15-7-9-26-11-14(15)27-20(32)17-18(25)29-31-10-8-16(21(22,23)24)28-19(17)31;19-18(20,21)13-4-8-28-16(26-13)14(15(22)27-28)17(29)25-11-9-24-7-3-12(11)30-10-1-5-23-6-2-10/h7-11,13-14H,3-6,12H2,1-2H3,(H2,26,30)(H,28,33);3-11H,12H2,1-2H3,(H2,26,30)(H,28,33);4-6,8,11,13H,2-3,7,9-10,12H2,1H3,(H2,25,29)(H,27,32);7-13H,3-6H2,1-2H3,(H2,25,29)(H,27,32);3-4,7-10,23H,1-2,5-6H2,(H2,22,27)(H,25,29)
InChIKeyNWLMZNMSWKBBQX-UHFFFAOYSA-N
MW2313.24 g/mol
LogP15.11
Rot. Bonds28

About 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 159905012) has the molecular formula C104H112F15N35O11 and a molecular weight of 2313.24 g/mol. Its IUPAC name is 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID159905012
Molecular FormulaC104H112F15N35O11
Molecular Weight2313.24 g/mol
Exact Mass2311.90
IUPAC Name2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCN(C)C1CCC(COc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)CC1.CN(C)C1CCC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)CC1.CN(C)Cc1ccc(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)cc1.COCCN1CCCC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OC1CCNCC1
InChIInChI=1S/C22H26F3N7O2.C22H20F3N7O2.C21H24F3N7O3.C21H24F3N7O2.C18H18F3N7O2/c1-31(2)14-5-3-13(4-6-14)12-34-16-7-9-27-11-15(16)28-21(33)18-19(26)30-32-10-8-17(22(23,24)25)29-20(18)32;1-31(2)12-13-3-5-14(6-4-13)34-16-7-9-27-11-15(16)28-21(33)18-19(26)30-32-10-8-17(22(23,24)25)29-20(18)32;1-33-10-9-30-7-2-3-13(12-30)34-15-4-6-26-11-14(15)27-20(32)17-18(25)29-31-8-5-16(21(22,23)24)28-19(17)31;1-30(2)12-3-5-13(6-4-12)33-15-7-9-26-11-14(15)27-20(32)17-18(25)29-31-10-8-16(21(22,23)24)28-19(17)31;19-18(20,21)13-4-8-28-16(26-13)14(15(22)27-28)17(29)25-11-9-24-7-3-12(11)30-10-1-5-23-6-2-10/h7-11,13-14H,3-6,12H2,1-2H3,(H2,26,30)(H,28,33);3-11H,12H2,1-2H3,(H2,26,30)(H,28,33);4-6,8,11,13H,2-3,7,9-10,12H2,1H3,(H2,25,29)(H,27,32);7-13H,3-6H2,1-2H3,(H2,25,29)(H,27,32);3-4,7-10,23H,1-2,5-6H2,(H2,22,27)(H,25,29)
InChIKeyNWLMZNMSWKBBQX-UHFFFAOYSA-N
XLogP15.11
TPSA571.37 Ų
H-Bond Donors11
H-Bond Acceptors41
Rotatable Bonds28
Heavy Atoms165
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002313.24
LogP ≤ 515.11
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1041

Analyze 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

US20240368194, Example 13
CID 167439846
US20240368194, Example 33
CID 172494536
2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 90444230
1-[4-(2-hydroxyethoxy)-N-[[4-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2,2,2-trifluoroethyl)pyrazolo[5,4-d]pyrimidin-6-yl]phenyl]carbamoyl]anilino]-1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-3-[4-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(2,2,2-trifluoroethyl)pyrazolo[5,4-d]pyrimidin-6-yl]phenyl]urea
CID 90738642
N-ethyl-2-[4-[[4-(4-ethylphenyl)-1-[[4-[[4-[4-[2-[4-[[4-(3-fluoro-4-propoxyphenyl)-5-methylpyrimidin-2-yl]amino]pyrazol-1-yl]acetyl]morpholin-3-yl]-6-[3-fluoro-4-(3,3,3-trifluoropropoxy)phenyl]-5-methylpyrimidin-2-yl]amino]pyrazol-1-yl]methyl]-5-methylpyrimidin-1-ium-2-yl]amino]pyrazol-1-yl]acetamide
CID 123292907
2-methyl-N-[6-[3-[(6-morpholin-4-ylpyridin-2-yl)carbamoyl]-6-[3-(trifluoromethyl)piperidin-1-yl]imidazo[1,2-b]pyridazin-8-yl]oxypyridin-2-yl]-5-[2-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 123457530
2-amino-N-[4-[[6-[(Z)-2-[[3-[[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]carbamoyl]-4-iminopentan-2-ylidene]amino]-3,3,3-trifluoroprop-1-enyl]-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 123884781
6-(3-fluoropyrrolidin-1-yl)-N-(6-morpholin-4-yl-2-pyridinyl)-8-[[6-[[5-[2-(trifluoromethyl)phenyl]-1-[[6-[[5-[2-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonyl]amino]-2-pyridinyl]oxy]pyrazolo[1,5-a]pyrimidin-1-ium-3-carbonyl]amino]-2-pyridinyl]oxymethyl]imidazo[1,2-b]pyridazine-3-carboxamide
CID 124017564
(3R,12S)-6-fluoro-12-(fluoromethyl)-19-[[[(3R,11R)-6-fluoro-3-methyl-14-oxo-10-oxa-2,13,17,18,21-pentazatetracyclo[13.5.2.04,9.018,22]docosa-1(21),4(9),5,7,15(22),16,19-heptaen-11-yl]methyl-methylamino]methyl]-3-methyl-10-oxa-2,13,17,18,21-pentazatetracyclo[13.5.2.04,9.018,22]docosa-1(21),4(9),5,7,15(22),16,19-heptaen-14-one
CID 137291197
7-(2,2-difluoroethoxy)-8-[6-(3,5-difluorophenyl)-3-[[[7-[(2-methyl-1,2,4-triazol-3-yl)methoxy]-1,5-naphthyridin-4-yl]amino]methyl]-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]-N-[[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]-1,5-naphthyridin-4-amine
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N-[[6-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]-8-[6-(1-methylpyrazol-4-yl)-3-[[[7-(2,2,2-trifluoroethoxy)-1,5-naphthyridin-4-yl]amino]methyl]-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]-7-(2-pyrazol-1-ylethoxy)-1,5-naphthyridin-4-amine
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N-(4,6-dimethyl-3-pyridinyl)-5-[2-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;ethane;N-(5-fluoro-3-pyridinyl)-5-[2-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 145564916

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 159905012) is 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is CN(C)C1CCC(COc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)CC1.CN(C)C1CCC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)CC1.CN(C)Cc1ccc(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)cc1.COCCN1CCCC(Oc2ccncc2NC(=O)c2c(N)nn3ccc(C(F)(F)F)nc23)C1.Nc1nn2ccc(C(F)(F)F)nc2c1C(=O)Nc1cnccc1OC1CCNCC1.
What is the InChIKey of 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is NWLMZNMSWKBBQX-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H26F3N7O2.C22H20F3N7O2.C21H24F3N7O3.C21H24F3N7O2.C18H18F3N7O2/c1-31(2)14-5-3-13(4-6-14)12-34-16-7-9-27-11-15(16)28-21(33)18-19(26)30-32-10-8-17(22(23,24)25)29-20(18)32;1-31(2)12-13-3-5-14(6-4-13)34-16-7-9-27-11-15(16)28-21(33)18-19(26)30-32-10-8-17(22(23,24)25)29-20(18)32;1-33-10-9-30-7-2-3-13(12-30)34-15-4-6-26-11-14(15)27-20(32)17-18(25)29-31-8-5-16(21(22,23)24)28-19(17)31;1-30(2)12-3-5-13(6-4-12)33-15-7-9-26-11-14(15)27-20(32)17-18(25)29-31-10-8-16(21(22,23)24)28-19(17)31;19-18(20,21)13-4-8-28-16(26-13)14(15(22)27-28)17(29)25-11-9-24-7-3-12(11)30-10-1-5-23-6-2-10/h7-11,13-14H,3-6,12H2,1-2H3,(H2,26,30)(H,28,33);3-11H,12H2,1-2H3,(H2,26,30)(H,28,33);4-6,8,11,13H,2-3,7,9-10,12H2,1H3,(H2,25,29)(H,27,32);7-13H,3-6H2,1-2H3,(H2,25,29)(H,27,32);3-4,7-10,23H,1-2,5-6H2,(H2,22,27)(H,25,29).
What are the key properties of 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2313.24 g/mol, XLogP of 15.11, 28 rotatable bonds, 11 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-[4-[[4-(dimethylamino)cyclohexyl]methoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[4-[(dimethylamino)methyl]phenoxy]-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[4-[1-(2-methoxyethyl)piperidin-3-yl]oxy-3-pyridinyl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-piperidin-4-yloxy-3-pyridinyl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 159905012), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).