3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine

C124H144N30O10 — CID 167570464

About 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine

3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine (PubChem CID 167570464) has the molecular formula C124H144N30O10 and a molecular weight of 2214.72 g/mol. Its IUPAC name is 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine.

Molecular Properties

• Compound Name: 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine
• PubChem CID: 167570464
• Molecular Formula: C124H144N30O10
• Molecular Weight: 2214.72 g/mol
• Exact Mass: 2213.17
• IUPAC Name: 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine
• SMILES: COc1c(N)ncc(C)c1COc1nc(-c2cc(C)c3c(c2)CN(C)CC3)cnc1N.COc1cc(-c2cnc(N)c(OCc3ccnc4[nH]ccc34)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OC3CC3)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OCC(C)C)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OCCc3ccccc3)n2)cc2c1CCN(C)C2
• InChI: InChI=1S/C29H32N6O2.C25H32N6O2.C24H28N6O2.C23H24N6O2.C23H28N6O2/c1-19-14-22(15-23-17-35(2)12-9-24(19)23)25-16-33-28(31)29(34-25)37-18-21-8-11-32-27(30)26(21)36-13-10-20-6-4-3-5-7-20;1-15(2)13-32-22-17(5-7-28-23(22)26)14-33-25-24(27)29-11-21(30-25)18-9-16(3)20-6-8-31(4)12-19(20)10-18;1-14-9-16(10-17-12-30(2)8-6-19(14)17)20-11-28-23(26)24(29-20)31-13-15-5-7-27-22(25)21(15)32-18-3-4-18;1-29-8-5-17-16(12-29)9-15(10-20(17)30-2)19-11-27-21(24)23(28-19)31-13-14-3-6-25-22-18(14)4-7-26-22;1-13-7-15(8-16-11-29(3)6-5-17(13)16)19-10-27-22(25)23(28-19)31-12-18-14(2)9-26-21(24)20(18)30-4/h3-8,11,14-16H,9-10,12-13,17-18H2,1-2H3,(H2,30,32)(H2,31,33);5,7,9-11,15H,6,8,12-14H2,1-4H3,(H2,26,28)(H2,27,29);5,7,9-11,18H,3-4,6,8,12-13H2,1-2H3,(H2,25,27)(H2,26,28);3-4,6-7,9-11H,5,8,12-13H2,1-2H3,(H2,24,27)(H,25,26);7-10H,5-6,11-12H2,1-4H3,(H2,24,26)(H2,25,27)
• InChIKey: FVNKOZFNJANOLI-UHFFFAOYSA-N
• XLogP: 17.01
• TPSA: 551.82 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 39
• Rotatable Bonds: 31
• Heavy Atoms: 164
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2214.72
LogP ≤ 5	17.01
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine?

The IUPAC name of 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine (CID 167570464) is 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine.

What is the SMILES notation for 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine?

The canonical SMILES for 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine is COc1c(N)ncc(C)c1COc1nc(-c2cc(C)c3c(c2)CN(C)CC3)cnc1N.COc1cc(-c2cnc(N)c(OCc3ccnc4[nH]ccc34)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OC3CC3)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OCC(C)C)n2)cc2c1CCN(C)C2.Cc1cc(-c2cnc(N)c(OCc3ccnc(N)c3OCCc3ccccc3)n2)cc2c1CCN(C)C2.

What is the InChIKey of 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine?

The InChIKey is FVNKOZFNJANOLI-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H32N6O2.C25H32N6O2.C24H28N6O2.C23H24N6O2.C23H28N6O2/c1-19-14-22(15-23-17-35(2)12-9-24(19)23)25-16-33-28(31)29(34-25)37-18-21-8-11-32-27(30)26(21)36-13-10-20-6-4-3-5-7-20;1-15(2)13-32-22-17(5-7-28-23(22)26)14-33-25-24(27)29-11-21(30-25)18-9-16(3)20-6-8-31(4)12-19(20)10-18;1-14-9-16(10-17-12-30(2)8-6-19(14)17)20-11-28-23(26)24(29-20)31-13-15-5-7-27-22(25)21(15)32-18-3-4-18;1-29-8-5-17-16(12-29)9-15(10-20(17)30-2)19-11-27-21(24)23(28-19)31-13-14-3-6-25-22-18(14)4-7-26-22;1-13-7-15(8-16-11-29(3)6-5-17(13)16)19-10-27-22(25)23(28-19)31-12-18-14(2)9-26-21(24)20(18)30-4/h3-8,11,14-16H,9-10,12-13,17-18H2,1-2H3,(H2,30,32)(H2,31,33);5,7,9-11,15H,6,8,12-14H2,1-4H3,(H2,26,28)(H2,27,29);5,7,9-11,18H,3-4,6,8,12-13H2,1-2H3,(H2,25,27)(H2,26,28);3-4,6-7,9-11H,5,8,12-13H2,1-2H3,(H2,24,27)(H,25,26);7-10H,5-6,11-12H2,1-4H3,(H2,24,26)(H2,25,27).

What are the key properties of 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine?

3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine has a molecular weight of 2214.72 g/mol, XLogP of 17.01, 31 rotatable bonds, 10 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 3-[(2-amino-3-cyclopropyloxy-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[(2-amino-3-methoxy-5-methyl-4-pyridinyl)methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-methylpropoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;3-[[2-amino-3-(2-phenylethoxy)-4-pyridinyl]methoxy]-5-(2,5-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)pyrazin-2-amine;5-(5-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)-3-(1H-pyrrolo[2,3-b]pyridin-4-ylmethoxy)pyrazin-2-amine is sourced from PubChem (CID 167570464), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).