4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide

C135H119F6N29O14S3 — CID 167643980

IUPAC4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide
SMILESCCOc1c(-c2cc(F)cc(F)c2)ccc(C(=O)N(C)Cc2cnc(CO)c3cn[nH]c23)c1F.CCOc1cc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)c(F)cc1-c1cccc(F)c1.CCOc1cc(C(=O)N(C)Cc2cnc(CO)c3cn[nH]c23)c(F)cc1-c1cccc(C#N)c1.CCOc1cc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1ccsc1.CCOc1nc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1ccsc1.CCOc1nc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1csc(C#N)c1
InChIInChI=1S/C25H22FN5O3.C24H21F3N4O3.C24H19F2N5O2.C21H18N6O2S.C21H20N4O2S.C20H19N5O2S/c1-3-34-23-9-19(21(26)8-18(23)16-6-4-5-15(7-16)10-27)25(33)31(2)13-17-11-28-22(14-32)20-12-29-30-24(17)20;1-3-34-23-17(13-6-15(25)8-16(26)7-13)4-5-18(21(23)27)24(33)31(2)11-14-9-28-20(12-32)19-10-29-30-22(14)19;1-3-33-22-9-18(20(26)8-17(22)14-5-4-6-16(25)7-14)24(32)31(2)13-15-11-28-21(10-27)19-12-29-30-23(15)19;1-3-29-20-17(13-6-16(7-22)30-12-13)4-5-18(25-20)21(28)27(2)11-15-9-23-8-14-10-24-26-19(14)15;1-3-27-19-8-14(4-5-18(19)15-6-7-28-13-15)21(26)25(2)12-17-10-22-9-16-11-23-24-20(16)17;1-3-27-19-16(13-6-7-28-12-13)4-5-17(23-19)20(26)25(2)11-15-9-21-8-14-10-22-24-18(14)15/h4-9,11-12,32H,3,13-14H2,1-2H3,(H,29,30);4-10,32H,3,11-12H2,1-2H3,(H,29,30);4-9,11-12H,3,13H2,1-2H3,(H,29,30);4-6,8-10,12H,3,11H2,1-2H3,(H,24,26);4-11,13H,3,12H2,1-2H3,(H,23,24);4-10,12H,3,11H2,1-2H3,(H,22,24)
InChIKeyPOPZNLDUKZILMD-UHFFFAOYSA-N
MW2581.81 g/mol
LogP24.18
Rot. Bonds38

About 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide

4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide (PubChem CID 167643980) has the molecular formula C135H119F6N29O14S3 and a molecular weight of 2581.81 g/mol. Its IUPAC name is 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide.

Molecular Properties

Compound Name4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide
PubChem CID167643980
Molecular FormulaC135H119F6N29O14S3
Molecular Weight2581.81 g/mol
Exact Mass2579.86
IUPAC Name4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide
SMILESCCOc1c(-c2cc(F)cc(F)c2)ccc(C(=O)N(C)Cc2cnc(CO)c3cn[nH]c23)c1F.CCOc1cc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)c(F)cc1-c1cccc(F)c1.CCOc1cc(C(=O)N(C)Cc2cnc(CO)c3cn[nH]c23)c(F)cc1-c1cccc(C#N)c1.CCOc1cc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1ccsc1.CCOc1nc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1ccsc1.CCOc1nc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1csc(C#N)c1
InChIInChI=1S/C25H22FN5O3.C24H21F3N4O3.C24H19F2N5O2.C21H18N6O2S.C21H20N4O2S.C20H19N5O2S/c1-3-34-23-9-19(21(26)8-18(23)16-6-4-5-15(7-16)10-27)25(33)31(2)13-17-11-28-22(14-32)20-12-29-30-24(17)20;1-3-34-23-17(13-6-15(25)8-16(26)7-13)4-5-18(21(23)27)24(33)31(2)11-14-9-28-20(12-32)19-10-29-30-22(14)19;1-3-33-22-9-18(20(26)8-17(22)14-5-4-6-16(25)7-14)24(32)31(2)13-15-11-28-21(10-27)19-12-29-30-23(15)19;1-3-29-20-17(13-6-16(7-22)30-12-13)4-5-18(25-20)21(28)27(2)11-15-9-23-8-14-10-24-26-19(14)15;1-3-27-19-8-14(4-5-18(19)15-6-7-28-13-15)21(26)25(2)12-17-10-22-9-16-11-23-24-20(16)17;1-3-27-19-16(13-6-7-28-12-13)4-5-17(23-19)20(26)25(2)11-15-9-21-8-14-10-22-24-18(14)15/h4-9,11-12,32H,3,13-14H2,1-2H3,(H,29,30);4-10,32H,3,11-12H2,1-2H3,(H,29,30);4-9,11-12H,3,13H2,1-2H3,(H,29,30);4-6,8-10,12H,3,11H2,1-2H3,(H,24,26);4-11,13H,3,12H2,1-2H3,(H,23,24);4-10,12H,3,11H2,1-2H3,(H,22,24)
InChIKeyPOPZNLDUKZILMD-UHFFFAOYSA-N
XLogP24.18
TPSA564.27 Ų
H-Bond Donors8
H-Bond Acceptors34
Rotatable Bonds38
Heavy Atoms187
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002581.81
LogP ≤ 524.18
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1034

Analyze 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-(2-amino-2-oxoethyl)-3-[3-[2-(2,2,3,3,3-pentafluoropropoxy)phenyl]phenyl]pyrazole-5-carboxamide;3-[3-(1-benzothiophen-7-yl)phenyl]-1H-pyrazole-5-carboxamide;3-[3-[5-fluoro-2-(2,2,3,3,3-pentafluoropropoxy)phenyl]phenyl]-1H-pyrazole-5-carboxamide;3-[3-[5-fluoro-2-(2,2,3,3,3-pentafluoropropoxy)phenyl]phenyl]-1H-pyrazole-5-carboxylic acid;3-[3-(2-phenylphenyl)phenyl]-1H-pyrazole-5-carboxamide;3-(3-pyridin-4-ylphenyl)-1H-pyrazole-5-carboxamide
CID 158276481
(2S)-N-[3-(5-acetylthiophen-2-yl)-1H-indazol-5-yl]-1-benzylpyrrolidine-2-carboxamide;(2S)-N-[3-(1-benzofuran-2-yl)-1H-indazol-5-yl]pyrrolidine-2-carboxamide;N-[3-(1-benzothiophen-2-yl)-1H-indazol-5-yl]-1-benzylpiperidine-4-carboxamide;(2S)-N-[3-(3-ethoxyphenyl)-1H-indazol-5-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]pyrrolidine-2-carboxamide;(3R)-3-hydroxy-3-phenyl-N-(3-pyridin-3-yl-1H-indazol-5-yl)propanamide;N-(3-naphthalen-2-yl-1H-indazol-5-yl)piperidine-4-carboxamide
CID 159622710
N-[(3R,6S)-6-(diethylcarbamoyl)-1-[(2-fluoro-6-methoxyphenyl)methyl]piperidin-3-yl]-3-(2-methylindazol-5-yl)-1H-indazole-5-carboxamide;N-[(3R,6S)-6-(diethylcarbamoyl)-1-(thiophen-2-ylmethyl)piperidin-3-yl]-3-(2-methyl-4-pyridinyl)-1H-indazole-5-carboxamide;N-[(3R,6S)-6-(3,3-difluoroazetidine-1-carbonyl)-1-[(2-fluoro-6-methoxyphenyl)methyl]piperidin-3-yl]-3-(2-methylindazol-5-yl)-1H-indazole-5-carboxamide;N-[(3R,6S)-6-(dimethylcarbamoyl)-1-[(2-fluoro-6-methoxyphenyl)methyl]piperidin-3-yl]-3-(2-methylindazol-5-yl)-1H-indazole-5-carboxamide
CID 160482393
2,5-dimethylfuran;1,4-dimethylpyrazole;2,4-dimethylpyridine;1,2-dimethylpyrrole;2,5-dimethylthiophene;ethane;2-ethyl-1-methylpyrrole;3-fluoro-1-methylpyrrolidine;(3R)-3-fluoro-1-methylpyrrolidine;(3S)-3-fluoro-1-methylpyrrolidine;1-methoxybut-2-ene;2-methyl-1-benzofuran;2-methylcyclopenta-1,3-diene;methylcyclopentane;1-methylcyclopentene;methylcyclopropane;5-methyl-2,3-dihydro-1-benzofuran;4-methyl-3,6-dihydro-2H-pyran;2-methyl-1H-indole;(3-methylphenyl)-pyrrolidin-1-ylmethanone;bis(1-methylpiperidine);1-methylpyrazole;5-methyl-1H-pyrazole;2-methylpyridine;6-methyl-1H-pyridin-2-one;bis(1-methylpyrrole);2-methyl-1H-pyrrole;5-methyl-3H-pyrrole;1-methylpyrrolidine;1-methylpyrrolidin-3-ol;(3S)-1-methylpyrrolidin-3-ol;(3R)-1-methylpyrrolidin-3-ol;2-methyl-1,3-thiazole;5-methyl-1,3-thiazole;5-methyl-2-(trifluoromethyl)pyridine;toluene;1,2,5-trimethylpyrrole
CID 160814217
2-(1-benzofuran-2-yl)-6-ethenylpyridine;2-[3-(1,1-difluoroethyl)phenyl]pyridine-3-carbaldehyde;6-[3-(1,1-difluoroethyl)phenyl]pyridine-2-carbaldehyde;2-[5-(1,1-difluoroethyl)thiophen-2-yl]pyridine-3-carbaldehyde;2-ethenyl-6-(furan-2-yl)pyridine;2-ethenyl-6-(furan-3-yl)pyridine;2-ethenyl-6-[2-(trifluoromethyl)phenyl]pyridine;2-ethenyl-6-[4-(trifluoromethyl)phenyl]pyridine;2-(furan-2-yl)pyridine-3-carbaldehyde;2-(furan-3-yl)pyridine-3-carbaldehyde;2-(1H-pyrazol-5-yl)pyridine-3-carbaldehyde;2-thiophen-3-ylpyridine-3-carbaldehyde;2-[2-(trifluoromethyl)phenyl]pyridine-3-carbaldehyde
CID 162168779
6-cyclopropyloxy-N-methyl-5-phenyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;3-(1,1-difluoroethoxy)-4-(3-fluorophenyl)-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)benzamide;3-(1,1-difluoroethoxy)-N-methyl-4-phenyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)benzamide;3-ethoxy-4-ethynyl-N-(1H-indazol-7-ylmethyl)-N-methylbenzamide;3-ethoxy-N-(1H-indazol-7-ylmethyl)-N-methyl-4-prop-1-ynylbenzamide
CID 167560068
(E)-4-[(3R)-3-[[5-[(Z)-2-(4-cyanophenyl)-4,4,4-trifluoro-1-(3-fluoro-2H-indazol-5-yl)but-1-enyl]-2-pyridinyl]oxy]piperidin-1-yl]-N,N-dimethylbut-2-enamide;4-[(Z)-1-[6-[(3R)-1-[(E)-4-(dimethylamino)-4-oxobut-2-enyl]piperidin-3-yl]oxy-3-pyridinyl]-4,4,4-trifluoro-1-(3-fluoro-2H-indazol-5-yl)but-1-en-2-yl]-N-methylbenzamide;(E)-N,N-dimethyl-4-[(3R)-3-[[5-[(Z)-4,4,4-trifluoro-1-(3-fluoro-2H-indazol-5-yl)-2-(4-methylsulfonylphenyl)but-1-enyl]-2-pyridinyl]oxy]piperidin-1-yl]but-2-enamide;(E)-N,N-dimethyl-4-[(3R)-3-[[5-[(Z)-4,4,4-trifluoro-1-(3-fluoro-2H-indazol-5-yl)-2-[4-(trifluoromethyl)phenyl]but-1-enyl]-2-pyridinyl]oxy]piperidin-1-yl]but-2-enamide;1-[(3R)-3-[[5-[(Z)-4,4,4-trifluoro-1-(3-fluoro-2H-indazol-5-yl)-2-phenylbut-1-enyl]-2-pyridinyl]oxy]piperidin-1-yl]but-2-yn-1-one
CID 167653284
4-(3-cyanophenyl)-3-cyclopropyloxy-N-[[4-(fluoromethyl)-1H-indazol-7-yl]methyl]-N-methylbenzamide;4-(3-cyanophenyl)-3-(1,1-difluoroethoxy)-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)benzamide;6-cyclopropyloxy-3-fluoro-N-[(4-fluoro-1H-indazol-7-yl)methyl]-N-methyl-5-phenylpyridine-2-carboxamide;3-cyclopropyloxy-N-[[4-(fluoromethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-4-(3-fluorophenyl)-N-methylbenzamide;6-cyclopropyloxy-5-(3-fluorophenyl)-N-[(4-methoxy-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-N-methylpyridine-2-carboxamide;5-[2-ethoxy-4-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl-methylcarbamoyl]phenyl]-2-fluoro-N-methylbenzamide
CID 167701277
[2-[[3-(hydroxymethyl)phenyl]methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]-(4-methylphenyl)methanone;[2-[[4-(hydroxymethyl)phenyl]methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]-(4-methylphenyl)methanone;1H-indol-3-yl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-[(2-methoxyphenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]-(4-methylphenyl)methanone;(4-methylphenyl)-[2-(pyridin-2-ylmethoxy)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-pyridin-2-ylmethanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-(3H-pyrrol-4-yl)methanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-thiophen-3-ylmethanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
CID 157819693
[2-[[3-(hydroxymethyl)phenyl]methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]-(4-methylphenyl)methanone;[2-[(2-methoxyphenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]-(4-methylphenyl)methanone;(4-methylphenyl)-[2-(pyridin-2-ylmethoxy)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-pyridin-2-ylmethanone;(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-thiophen-3-ylmethanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
CID 158189028
N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
CID 159780855
bis(N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide);N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-pyridin-4-ylthieno[2,3-b]pyridine-2-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(propan-2-ylcarbamoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
CID 159927144

Frequently Asked Questions

What is the IUPAC name of 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide?
The IUPAC name of 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide (CID 167643980) is 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide.
What is the SMILES notation for 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide?
The canonical SMILES for 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide is CCOc1c(-c2cc(F)cc(F)c2)ccc(C(=O)N(C)Cc2cnc(CO)c3cn[nH]c23)c1F.CCOc1cc(C(=O)N(C)Cc2cnc(C#N)c3cn[nH]c23)c(F)cc1-c1cccc(F)c1.CCOc1cc(C(=O)N(C)Cc2cnc(CO)c3cn[nH]c23)c(F)cc1-c1cccc(C#N)c1.CCOc1cc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1ccsc1.CCOc1nc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1ccsc1.CCOc1nc(C(=O)N(C)Cc2cncc3cn[nH]c23)ccc1-c1csc(C#N)c1.
What is the InChIKey of 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide?
The InChIKey is POPZNLDUKZILMD-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H22FN5O3.C24H21F3N4O3.C24H19F2N5O2.C21H18N6O2S.C21H20N4O2S.C20H19N5O2S/c1-3-34-23-9-19(21(26)8-18(23)16-6-4-5-15(7-16)10-27)25(33)31(2)13-17-11-28-22(14-32)20-12-29-30-24(17)20;1-3-34-23-17(13-6-15(25)8-16(26)7-13)4-5-18(21(23)27)24(33)31(2)11-14-9-28-20(12-32)19-10-29-30-22(14)19;1-3-33-22-9-18(20(26)8-17(22)14-5-4-6-16(25)7-14)24(32)31(2)13-15-11-28-21(10-27)19-12-29-30-23(15)19;1-3-29-20-17(13-6-16(7-22)30-12-13)4-5-18(25-20)21(28)27(2)11-15-9-23-8-14-10-24-26-19(14)15;1-3-27-19-8-14(4-5-18(19)15-6-7-28-13-15)21(26)25(2)12-17-10-22-9-16-11-23-24-20(16)17;1-3-27-19-16(13-6-7-28-12-13)4-5-17(23-19)20(26)25(2)11-15-9-21-8-14-10-22-24-18(14)15/h4-9,11-12,32H,3,13-14H2,1-2H3,(H,29,30);4-10,32H,3,11-12H2,1-2H3,(H,29,30);4-9,11-12H,3,13H2,1-2H3,(H,29,30);4-6,8-10,12H,3,11H2,1-2H3,(H,24,26);4-11,13H,3,12H2,1-2H3,(H,23,24);4-10,12H,3,11H2,1-2H3,(H,22,24).
What are the key properties of 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide?
4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide has a molecular weight of 2581.81 g/mol, XLogP of 24.18, 38 rotatable bonds, 8 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(3-cyanophenyl)-5-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;N-[(4-cyano-1H-pyrazolo[4,5-c]pyridin-7-yl)methyl]-5-ethoxy-2-fluoro-4-(3-fluorophenyl)-N-methylbenzamide;5-(5-cyanothiophen-3-yl)-6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)pyridine-2-carboxamide;4-(3,5-difluorophenyl)-3-ethoxy-2-fluoro-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide;3-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-4-thiophen-3-ylbenzamide;6-ethoxy-N-methyl-N-(1H-pyrazolo[4,3-c]pyridin-7-ylmethyl)-5-thiophen-3-ylpyridine-2-carboxamide is sourced from PubChem (CID 167643980), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).