N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide

C151H187F13N16O15 — CID 173297610

IUPACN-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide
SMILESCOc1cc(N)cc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.COc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1.Cc1cc(N)nc(N2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.Cc1ccc(CN2CCC(NC(=O)[C@](O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)o1.Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.Nc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1F
InChIInChI=1S/C26H33F2N3O3.C26H32F2N2O3.C26H32F2N2O2.C25H30F3N3O2.C24H30F2N4O2.C24H30F2N2O3/c1-34-23-14-18(13-21(29)15-23)17-31-11-8-22(9-12-31)30-24(32)26(33,19-5-3-2-4-6-19)20-7-10-25(27,28)16-20;1-33-23-9-7-19(8-10-23)18-30-15-12-22(13-16-30)29-24(31)26(32,20-5-3-2-4-6-20)21-11-14-25(27,28)17-21;1-19-6-5-7-20(16-19)18-30-14-11-23(12-15-30)29-24(31)26(32,21-8-3-2-4-9-21)22-10-13-25(27,28)17-22;26-21-14-17(6-7-22(21)29)16-31-12-9-20(10-13-31)30-23(32)25(33,18-4-2-1-3-5-18)19-8-11-24(27,28)15-19;1-16-13-20(27)29-21(14-16)30-11-8-19(9-12-30)28-22(31)24(32,17-5-3-2-4-6-17)18-7-10-23(25,26)15-18;1-17-7-8-21(31-17)16-28-13-10-20(11-14-28)27-22(29)24(30,18-5-3-2-4-6-18)19-9-12-23(25,26)15-19/h2-6,13-15,20,22,33H,7-12,16-17,29H2,1H3,(H,30,32);2-10,21-22,32H,11-18H2,1H3,(H,29,31);2-9,16,22-23,32H,10-15,17-18H2,1H3,(H,29,31);1-7,14,19-20,33H,8-13,15-16,29H2,(H,30,32);2-6,13-14,18-19,32H,7-12,15H2,1H3,(H2,27,29)(H,28,31);2-8,19-20,30H,9-16H2,1H3,(H,27,29)/t20-,26?;21-,26?;22-,26?;19-,25?;18-,24?;19-,24+/m111111/s1
InChIKeyMWQPYAJBHRRKJN-AYVYIQGJSA-N
MW2713.23 g/mol
LogP23.36
Rot. Bonds37

About N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide

N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide (PubChem CID 173297610) has the molecular formula C151H187F13N16O15 and a molecular weight of 2713.23 g/mol. Its IUPAC name is N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide.

Molecular Properties

Compound NameN-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide
PubChem CID173297610
Molecular FormulaC151H187F13N16O15
Molecular Weight2713.23 g/mol
Exact Mass2711.42
IUPAC NameN-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide
SMILESCOc1cc(N)cc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.COc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1.Cc1cc(N)nc(N2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.Cc1ccc(CN2CCC(NC(=O)[C@](O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)o1.Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.Nc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1F
InChIInChI=1S/C26H33F2N3O3.C26H32F2N2O3.C26H32F2N2O2.C25H30F3N3O2.C24H30F2N4O2.C24H30F2N2O3/c1-34-23-14-18(13-21(29)15-23)17-31-11-8-22(9-12-31)30-24(32)26(33,19-5-3-2-4-6-19)20-7-10-25(27,28)16-20;1-33-23-9-7-19(8-10-23)18-30-15-12-22(13-16-30)29-24(31)26(32,20-5-3-2-4-6-20)21-11-14-25(27,28)17-21;1-19-6-5-7-20(16-19)18-30-14-11-23(12-15-30)29-24(31)26(32,21-8-3-2-4-9-21)22-10-13-25(27,28)17-22;26-21-14-17(6-7-22(21)29)16-31-12-9-20(10-13-31)30-23(32)25(33,18-4-2-1-3-5-18)19-8-11-24(27,28)15-19;1-16-13-20(27)29-21(14-16)30-11-8-19(9-12-30)28-22(31)24(32,17-5-3-2-4-6-17)18-7-10-23(25,26)15-18;1-17-7-8-21(31-17)16-28-13-10-20(11-14-28)27-22(29)24(30,18-5-3-2-4-6-18)19-9-12-23(25,26)15-19/h2-6,13-15,20,22,33H,7-12,16-17,29H2,1H3,(H,30,32);2-10,21-22,32H,11-18H2,1H3,(H,29,31);2-9,16,22-23,32H,10-15,17-18H2,1H3,(H,29,31);1-7,14,19-20,33H,8-13,15-16,29H2,(H,30,32);2-6,13-14,18-19,32H,7-12,15H2,1H3,(H2,27,29)(H,28,31);2-8,19-20,30H,9-16H2,1H3,(H,27,29)/t20-,26?;21-,26?;22-,26?;19-,25?;18-,24?;19-,24+/m111111/s1
InChIKeyMWQPYAJBHRRKJN-AYVYIQGJSA-N
XLogP23.36
TPSA437.97 Ų
H-Bond Donors15
H-Bond Acceptors25
Rotatable Bonds37
Heavy Atoms195
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002713.23
LogP ≤ 523.36
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1025

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'aniline', 'substructure': 'N/A'}

Analyze N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide with MolForge

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Related Compounds

(2R)-N-[1-[(4-amino-3-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
CID 54111593
N-[1-[(3,5-diaminophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
CID 174397651
(2R)-N-(1-benzylpiperidin-4-yl)-2-(3,3-difluorocyclopentyl)-2-hydroxy-2-phenylacetamide
CID 102016686
(2R)-N-[1-[(6-amino-4-chloro-2-pyridinyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
CID 54314105
(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-hydroxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide
CID 10646948
(2R)-N-[1-[(6-amino-2-pyridinyl)methyl]piperidin-4-yl]-2-(3,3-difluorocyclohexyl)-2-hydroxy-2-phenylacetamide
CID 54093625
(2R)-N-[1-[(6-amino-2-pyridinyl)methyl]-1-methylpiperidin-1-ium-4-yl]-2-(3,3-difluorocyclopentyl)-2-hydroxy-2-phenylacetamide
CID 10326009
N-[1-[(3-methoxyphenyl)methyl]piperidin-4-yl]-1-benzofuran-2-carboxamide
CID 67943148
N-(1-benzylpiperidin-4-yl)-1-[(5-methylfuran-2-yl)methyl]aziridine-2-carboxamide
CID 3445666
N-(1-benzylpiperidin-4-yl)-2-(3-methylphenyl)acetamide
CID 6465155
1-(3-bromophenyl)-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]cyclopropane-1-carboxamide
CID 55745166
2-cyclopentyl-2-hydroxy-N-[1-[[4-(hydroxymethyl)-2-pyridinyl]methyl]piperidin-4-yl]-2-phenylacetamide
CID 23289921

Frequently Asked Questions

What is the IUPAC name of N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide?
The IUPAC name of N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide (CID 173297610) is N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide.
What is the SMILES notation for N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide?
The canonical SMILES for N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide is COc1cc(N)cc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.COc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1.Cc1cc(N)nc(N2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.Cc1ccc(CN2CCC(NC(=O)[C@](O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)o1.Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)c1.Nc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)[C@@H]3CCC(F)(F)C3)CC2)cc1F.
What is the InChIKey of N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide?
The InChIKey is MWQPYAJBHRRKJN-AYVYIQGJSA-N. The full InChI is InChI=1S/C26H33F2N3O3.C26H32F2N2O3.C26H32F2N2O2.C25H30F3N3O2.C24H30F2N4O2.C24H30F2N2O3/c1-34-23-14-18(13-21(29)15-23)17-31-11-8-22(9-12-31)30-24(32)26(33,19-5-3-2-4-6-19)20-7-10-25(27,28)16-20;1-33-23-9-7-19(8-10-23)18-30-15-12-22(13-16-30)29-24(31)26(32,20-5-3-2-4-6-20)21-11-14-25(27,28)17-21;1-19-6-5-7-20(16-19)18-30-14-11-23(12-15-30)29-24(31)26(32,21-8-3-2-4-9-21)22-10-13-25(27,28)17-22;26-21-14-17(6-7-22(21)29)16-31-12-9-20(10-13-31)30-23(32)25(33,18-4-2-1-3-5-18)19-8-11-24(27,28)15-19;1-16-13-20(27)29-21(14-16)30-11-8-19(9-12-30)28-22(31)24(32,17-5-3-2-4-6-17)18-7-10-23(25,26)15-18;1-17-7-8-21(31-17)16-28-13-10-20(11-14-28)27-22(29)24(30,18-5-3-2-4-6-18)19-9-12-23(25,26)15-19/h2-6,13-15,20,22,33H,7-12,16-17,29H2,1H3,(H,30,32);2-10,21-22,32H,11-18H2,1H3,(H,29,31);2-9,16,22-23,32H,10-15,17-18H2,1H3,(H,29,31);1-7,14,19-20,33H,8-13,15-16,29H2,(H,30,32);2-6,13-14,18-19,32H,7-12,15H2,1H3,(H2,27,29)(H,28,31);2-8,19-20,30H,9-16H2,1H3,(H,27,29)/t20-,26?;21-,26?;22-,26?;19-,25?;18-,24?;19-,24+/m111111/s1.
What are the key properties of N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide?
N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide has a molecular weight of 2713.23 g/mol, XLogP of 23.36, 37 rotatable bonds, 15 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-[(3-amino-5-methoxyphenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;N-[1-(6-amino-4-methyl-2-pyridinyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-2-phenylacetamide;(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]-2-phenylacetamide;2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-N-[1-[(3-methylphenyl)methyl]piperidin-4-yl]-2-phenylacetamide is sourced from PubChem (CID 173297610), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).