N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide

C48H58N16O5Si — CID 174054630

IUPACN-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide
SMILESC[C@H]1CC[C@H](c2ccc3[nH]ncc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn(COCC[Si](C)(C)C)nc23)C1.C[C@H]1CC[C@H](c2ccc3[nH]ncc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn[nH]c23)C1
InChIInChI=1S/C27H36N8O3Si.C21H22N8O2/c1-17-5-8-23(18-6-7-21-19(11-18)12-30-32-21)35(14-17)27(37)26(36)31-22-13-29-25(28)20-15-34(33-24(20)22)16-38-9-10-39(2,3)4;1-11-2-5-17(12-3-4-15-13(6-12)7-24-27-15)29(10-11)21(31)20(30)26-16-9-23-19(22)14-8-25-28-18(14)16/h6-7,11-13,15,17,23H,5,8-10,14,16H2,1-4H3,(H2,28,29)(H,30,32)(H,31,36);3-4,6-9,11,17H,2,5,10H2,1H3,(H2,22,23)(H,24,27)(H,25,28)(H,26,30)/t17-,23+;11-,17+/m00/s1
InChIKeyCUGKNHKFHJMSQY-PHTKZKACSA-N
MW967.18 g/mol
LogP6.50
Rot. Bonds9

About N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide

N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide (PubChem CID 174054630) has the molecular formula C48H58N16O5Si and a molecular weight of 967.18 g/mol. Its IUPAC name is N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide.

Molecular Properties

Compound NameN-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide
PubChem CID174054630
Molecular FormulaC48H58N16O5Si
Molecular Weight967.18 g/mol
Exact Mass966.45
IUPAC NameN-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide
SMILESC[C@H]1CC[C@H](c2ccc3[nH]ncc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn(COCC[Si](C)(C)C)nc23)C1.C[C@H]1CC[C@H](c2ccc3[nH]ncc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn[nH]c23)C1
InChIInChI=1S/C27H36N8O3Si.C21H22N8O2/c1-17-5-8-23(18-6-7-21-19(11-18)12-30-32-21)35(14-17)27(37)26(36)31-22-13-29-25(28)20-15-34(33-24(20)22)16-38-9-10-39(2,3)4;1-11-2-5-17(12-3-4-15-13(6-12)7-24-27-15)29(10-11)21(31)20(30)26-16-9-23-19(22)14-8-25-28-18(14)16/h6-7,11-13,15,17,23H,5,8-10,14,16H2,1-4H3,(H2,28,29)(H,30,32)(H,31,36);3-4,6-9,11,17H,2,5,10H2,1H3,(H2,22,23)(H,24,27)(H,25,28)(H,26,30)/t17-,23+;11-,17+/m00/s1
InChIKeyCUGKNHKFHJMSQY-PHTKZKACSA-N
XLogP6.50
TPSA289.73 Ų
H-Bond Donors7
H-Bond Acceptors14
Rotatable Bonds9
Heavy Atoms70
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 500967.18
LogP ≤ 56.50
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1014

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'diketo_group', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Analyze N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-5-methyl-2-quinolin-6-ylpiperidin-1-yl]-2-oxoacetamide
CID 169114683
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[5-methyl-2-(6-methyl-3-pyridinyl)piperidin-1-yl]-2-oxoacetamide
CID 169113542
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[5-methyl-2-(1,1,2-trimethyl-3,4-dihydroisoquinolin-6-yl)piperidin-1-yl]-2-oxoacetamide
CID 169113958
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-[4-[(dimethylamino)methyl]phenyl]-5-methylpiperidin-1-yl]-2-oxoacetamide
CID 169113098
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[2-[3-[2-(dimethylamino)ethyl]phenyl]-5-methylpiperidin-1-yl]-2-oxoacetamide
CID 169114336
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2S,5S)-5-methyl-2-(1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoacetamide
CID 169113862
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-[4-[2-[iodo(methyl)amino]ethyl]phenyl]-5-methylpiperidin-1-yl]-2-oxoacetamide
CID 170067745
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-(5-methyl-2-thiophen-2-ylpiperidin-1-yl)-2-oxoacetamide
CID 169113607
N-[4-amino-1-(2-trimethylsilylethoxymethyl)pyrazolo[4,5-c]pyridin-7-yl]-2-[(2R,5S)-5-methyl-2-(6-methyl-3-pyridinyl)piperidin-1-yl]-2-oxoacetamide
CID 169113136
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-cyclopropyl-5-methylpiperidin-1-yl]-2-oxoacetamide
CID 169115092
N-[4-amino-1-(2-trimethylsilylethoxymethyl)pyrazolo[4,5-c]pyridin-7-yl]-2-[5-methyl-2-[2-oxo-1-(2-trimethylsilylethoxymethyl)-3,4-dihydroquinolin-6-yl]piperidin-1-yl]-2-oxoacetamide
CID 169114561
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[2-(4-fluorophenyl)-4-methoxy-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-1-(2-trimethylsilylethoxymethyl)pyrazolo[4,5-c]pyridin-7-yl]-2-[2-(4-fluorophenyl)-4-methoxy-5-methylpiperidin-1-yl]-2-oxoacetamide
CID 174054598

Frequently Asked Questions

What is the IUPAC name of N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide?
The IUPAC name of N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide (CID 174054630) is N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide.
What is the SMILES notation for N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide?
The canonical SMILES for N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide is C[C@H]1CC[C@H](c2ccc3[nH]ncc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn(COCC[Si](C)(C)C)nc23)C1.C[C@H]1CC[C@H](c2ccc3[nH]ncc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn[nH]c23)C1.
What is the InChIKey of N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide?
The InChIKey is CUGKNHKFHJMSQY-PHTKZKACSA-N. The full InChI is InChI=1S/C27H36N8O3Si.C21H22N8O2/c1-17-5-8-23(18-6-7-21-19(11-18)12-30-32-21)35(14-17)27(37)26(36)31-22-13-29-25(28)20-15-34(33-24(20)22)16-38-9-10-39(2,3)4;1-11-2-5-17(12-3-4-15-13(6-12)7-24-27-15)29(10-11)21(31)20(30)26-16-9-23-19(22)14-8-25-28-18(14)16/h6-7,11-13,15,17,23H,5,8-10,14,16H2,1-4H3,(H2,28,29)(H,30,32)(H,31,36);3-4,6-9,11,17H,2,5,10H2,1H3,(H2,22,23)(H,24,27)(H,25,28)(H,26,30)/t17-,23+;11-,17+/m00/s1.
What are the key properties of N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide?
N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide has a molecular weight of 967.18 g/mol, XLogP of 6.50, 9 rotatable bonds, 7 hydrogen bond donors, and 14 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-amino-1H-pyrazolo[4,5-c]pyridin-7-yl)-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide;N-[4-amino-2-(2-trimethylsilylethoxymethyl)pyrazolo[4,3-c]pyridin-7-yl]-2-[(2R,5S)-2-(1H-indazol-5-yl)-5-methylpiperidin-1-yl]-2-oxoacetamide is sourced from PubChem (CID 174054630), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).