(4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide

C40H39F4N7O4 — CID 176733803

IUPAC(4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide
SMILESCCN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(C(=O)N(C)[C@@H](C#N)CCN3CC4CCC(C3)O4)nn(-c3ccccc3)c21
InChIInChI=1S/C40H39F4N7O4/c1-3-50-37-33(32(24-12-14-27(41)15-13-24)34(39(50)54)46-36(52)25-8-7-9-26(20-25)40(42,43)44)35(47-51(37)28-10-5-4-6-11-28)38(53)48(2)29(21-45)18-19-49-22-30-16-17-31(23-49)55-30/h4-15,20,29-32,34H,3,16-19,22-23H2,1-2H3,(H,46,52)/t29-,30?,31?,32+,34+/m1/s1
InChIKeyIQNKFFYOLXMRRP-BZDJXQFZSA-N
MW757.79 g/mol
LogP5.54
Rot. Bonds10

About (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide

(4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide (PubChem CID 176733803) has the molecular formula C40H39F4N7O4 and a molecular weight of 757.79 g/mol. Its IUPAC name is (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide.

Molecular Properties

Compound Name(4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide
PubChem CID176733803
Molecular FormulaC40H39F4N7O4
Molecular Weight757.79 g/mol
Exact Mass757.30
IUPAC Name(4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide
SMILESCCN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(C(=O)N(C)[C@@H](C#N)CCN3CC4CCC(C3)O4)nn(-c3ccccc3)c21
InChIInChI=1S/C40H39F4N7O4/c1-3-50-37-33(32(24-12-14-27(41)15-13-24)34(39(50)54)46-36(52)25-8-7-9-26(20-25)40(42,43)44)35(47-51(37)28-10-5-4-6-11-28)38(53)48(2)29(21-45)18-19-49-22-30-16-17-31(23-49)55-30/h4-15,20,29-32,34H,3,16-19,22-23H2,1-2H3,(H,46,52)/t29-,30?,31?,32+,34+/m1/s1
InChIKeyIQNKFFYOLXMRRP-BZDJXQFZSA-N
XLogP5.54
TPSA123.80 Ų
H-Bond Donors1
H-Bond Acceptors8
Rotatable Bonds10
Heavy Atoms55
Complexity

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 500757.79
LogP ≤ 55.54
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 108

Analyze (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide?
The IUPAC name of (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide (CID 176733803) is (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide.
What is the SMILES notation for (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide?
The canonical SMILES for (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide is CCN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(C(=O)N(C)[C@@H](C#N)CCN3CC4CCC(C3)O4)nn(-c3ccccc3)c21.
What is the InChIKey of (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide?
The InChIKey is IQNKFFYOLXMRRP-BZDJXQFZSA-N. The full InChI is InChI=1S/C40H39F4N7O4/c1-3-50-37-33(32(24-12-14-27(41)15-13-24)34(39(50)54)46-36(52)25-8-7-9-26(20-25)40(42,43)44)35(47-51(37)28-10-5-4-6-11-28)38(53)48(2)29(21-45)18-19-49-22-30-16-17-31(23-49)55-30/h4-15,20,29-32,34H,3,16-19,22-23H2,1-2H3,(H,46,52)/t29-,30?,31?,32+,34+/m1/s1.
What are the key properties of (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide?
(4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide has a molecular weight of 757.79 g/mol, XLogP of 5.54, 10 rotatable bonds, 1 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for (4S,5S)-N-[(1R)-1-cyano-3-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)propyl]-7-ethyl-4-(4-fluorophenyl)-N-methyl-6-oxo-1-phenyl-5-[[3-(trifluoromethyl)benzoyl]amino]-4,5-dihydropyrazolo[5,4-b]pyridine-3-carboxamide is sourced from PubChem (CID 176733803), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).