6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine

C10H6ClF3N4 — CID 178073535

IUPAC6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine
SMILESNc1nc(-c2cnc(C(F)F)c(Cl)n2)ccc1F
InChIInChI=1S/C10H6ClF3N4/c11-8-7(9(13)14)16-3-6(17-8)5-2-1-4(12)10(15)18-5/h1-3,9H,(H2,15,18)
InChIKeyBUQWDYZEQZCHOZ-UHFFFAOYSA-N
MW274.63 g/mol
LogP2.85
Rot. Bonds2

About 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine

6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine (PubChem CID 178073535) has the molecular formula C10H6ClF3N4 and a molecular weight of 274.63 g/mol. Its IUPAC name is 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine.

Molecular Properties

Compound Name6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine
PubChem CID178073535
Molecular FormulaC10H6ClF3N4
Molecular Weight274.63 g/mol
Exact Mass274.02
IUPAC Name6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine
SMILESNc1nc(-c2cnc(C(F)F)c(Cl)n2)ccc1F
InChIInChI=1S/C10H6ClF3N4/c11-8-7(9(13)14)16-3-6(17-8)5-2-1-4(12)10(15)18-5/h1-3,9H,(H2,15,18)
InChIKeyBUQWDYZEQZCHOZ-UHFFFAOYSA-N
XLogP2.85
TPSA64.69 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds2
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500274.63
LogP ≤ 52.85
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

6-[6-chloro-5-(trifluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine
CID 178073443
3-chloro-5-(4-chloro-2-fluoro-3-methoxyphenyl)-2-(difluoromethyl)pyrazine
CID 178073048
5-chloro-3-(difluoromethyl)pyrazin-2-amine
CID 118609708
5-chloro-2-(difluoromethyl)pyridin-3-amine
CID 130094579
2-(difluoromethyl)-3,5-difluoropyridin-4-amine
CID 118812171
5-amino-4-chloro-2-(difluoromethyl)pyridin-3-ol
CID 130102480
2-chloro-3-fluoro-6-pyridin-2-ylpyridine
CID 175788383
1-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-4,4-difluoropiperidin-2-one
CID 178072932
3,5-dichloro-2-(difluoromethyl)pyridine
CID 60622989
6-(difluoromethyl)-5-fluoropyridine-2,3-diamine
CID 130098596
6-amino-2-(difluoromethyl)-5-fluoropyridine-3-carbaldehyde
CID 119014251
5-(5-chloro-2-pyridinyl)pyrazine-2,3-dicarboxamide
CID 69352567

Frequently Asked Questions

What is the IUPAC name of 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine?
The IUPAC name of 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine (CID 178073535) is 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine.
What is the SMILES notation for 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine?
The canonical SMILES for 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine is Nc1nc(-c2cnc(C(F)F)c(Cl)n2)ccc1F.
What is the InChIKey of 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine?
The InChIKey is BUQWDYZEQZCHOZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H6ClF3N4/c11-8-7(9(13)14)16-3-6(17-8)5-2-1-4(12)10(15)18-5/h1-3,9H,(H2,15,18).
What are the key properties of 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine?
6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine has a molecular weight of 274.63 g/mol, XLogP of 2.85, 2 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[6-chloro-5-(difluoromethyl)pyrazin-2-yl]-3-fluoropyridin-2-amine is sourced from PubChem (CID 178073535), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).