N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide

C20H16F2N2O4 — CID 18269394

IUPACN-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide
SMILESCOc1ccc(-c2cc(NC(=O)c3ccc[nH]c3=O)ccc2OC(F)F)cc1
InChIInChI=1S/C20H16F2N2O4/c1-27-14-7-4-12(5-8-14)16-11-13(6-9-17(16)28-20(21)22)24-19(26)15-3-2-10-23-18(15)25/h2-11,20H,1H3,(H,23,25)(H,24,26)
InChIKeyGTAISROMLWWSCM-UHFFFAOYSA-N
MW386.35 g/mol
LogP3.90
Rot. Bonds6

About N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide

N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide (PubChem CID 18269394) has the molecular formula C20H16F2N2O4 and a molecular weight of 386.35 g/mol. Its IUPAC name is N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide
PubChem CID18269394
Molecular FormulaC20H16F2N2O4
Molecular Weight386.35 g/mol
Exact Mass386.11
IUPAC NameN-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide
SMILESCOc1ccc(-c2cc(NC(=O)c3ccc[nH]c3=O)ccc2OC(F)F)cc1
InChIInChI=1S/C20H16F2N2O4/c1-27-14-7-4-12(5-8-14)16-11-13(6-9-17(16)28-20(21)22)24-19(26)15-3-2-10-23-18(15)25/h2-11,20H,1H3,(H,23,25)(H,24,26)
InChIKeyGTAISROMLWWSCM-UHFFFAOYSA-N
XLogP3.90
TPSA80.42 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds6
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500386.35
LogP ≤ 53.90
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

(6S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-[3-(trifluoromethyl)propoxy]phenyl]-6-trifluoromethyl-1,2,5,6-tetrahydropyridine-3-carboxamide
CID 71582673
N-[3-Benzyl-4-(3-isopropylamino-propoxy)-phenyl]-propionamide
CID 10316137
6-methoxy-3-[(4-methoxyanilino)methyl]-1H-quinolin-2-one
CID 664029
3-[(3,4-Dimethyl-phenylamino)-methyl]-6-methoxy-quinolin-2-ol
CID 939029
6-Methoxy-3-phenylaminomethyl-quinolin-2-ol
CID 942126
6-methoxy-3-[(3-methylanilino)methyl]-1H-quinolin-2-one
CID 943158
4-hydroxy-N-(4-methoxyphenethyl)-2-oxo-1,2-dihydroquinoline-3-carboxamide
CID 54683795
(2S)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide
CID 71581778
N-(4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide
CID 73348048
N'-(4-methoxy-3-methylphenyl)-N-[2-(4-methoxyphenyl)ethyl]oxamide
CID 121478721
N-[5-methyl-2-propan-2-yl-4-[4-(trifluoromethyl)phenoxy]phenyl]-2-oxo-1H-pyrazolo[1,5-a]pyridine-3-carboxamide
CID 163299001
N-(4-methoxyphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]propanamide
CID 763257

Frequently Asked Questions

What is the IUPAC name of N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide?
The IUPAC name of N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide (CID 18269394) is N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide.
What is the SMILES notation for N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide?
The canonical SMILES for N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide is COc1ccc(-c2cc(NC(=O)c3ccc[nH]c3=O)ccc2OC(F)F)cc1.
What is the InChIKey of N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide?
The InChIKey is GTAISROMLWWSCM-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H16F2N2O4/c1-27-14-7-4-12(5-8-14)16-11-13(6-9-17(16)28-20(21)22)24-19(26)15-3-2-10-23-18(15)25/h2-11,20H,1H3,(H,23,25)(H,24,26).
What are the key properties of N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide?
N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide has a molecular weight of 386.35 g/mol, XLogP of 3.90, 6 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(difluoromethoxy)-3-(4-methoxyphenyl)phenyl]-2-oxo-1H-pyridine-3-carboxamide is sourced from PubChem (CID 18269394), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).