6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide

C26H26N4O3 — CID 25031636

IUPAC6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide
SMILESCNC(=O)c1cccc2cc(Nc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12
InChIInChI=1S/C26H26N4O3/c1-28-25(31)19-5-3-4-16-12-17(6-7-18(16)19)30-21-8-11-29-22-14-24(23(32-2)13-20(21)22)33-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,31)(H,29,30)
InChIKeyMKPCPZGLIQMTQH-UHFFFAOYSA-N
MW442.52 g/mol
LogP4.37
Rot. Bonds7

About 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide

6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide (PubChem CID 25031636) has the molecular formula C26H26N4O3 and a molecular weight of 442.52 g/mol. Its IUPAC name is 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide.

Molecular Properties

Compound Name6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide
PubChem CID25031636
Molecular FormulaC26H26N4O3
Molecular Weight442.52 g/mol
Exact Mass442.20
IUPAC Name6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide
SMILESCNC(=O)c1cccc2cc(Nc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12
InChIInChI=1S/C26H26N4O3/c1-28-25(31)19-5-3-4-16-12-17(6-7-18(16)19)30-21-8-11-29-22-14-24(23(32-2)13-20(21)22)33-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,31)(H,29,30)
InChIKeyMKPCPZGLIQMTQH-UHFFFAOYSA-N
XLogP4.37
TPSA98.50 Ų
H-Bond Donors3
H-Bond Acceptors6
Rotatable Bonds7
Heavy Atoms33
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500442.52
LogP ≤ 54.37
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 106

Analyze 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide with MolForge

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Related Compounds

6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide
CID 25031916
benzyl N-[1-[[6-methoxy-4-[5-(methylcarbamoyl)naphthalen-2-yl]oxyquinolin-7-yl]oxymethyl]cyclopropyl]carbamate
CID 24905361
6-(6-methoxy-7-phenylmethoxyquinolin-4-yl)oxy-N-methylnaphthalene-1-carboxamide
CID 67276786
7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxy-N-(2-methyl-1H-indol-5-yl)quinolin-4-amine
CID 25016622
6-[7-[[1-(hydroxymethyl)cyclopropyl]amino]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide
CID 155077042
N-(6,7-dimethoxyquinolin-4-yl)oxynaphthalene-1-carboxamide
CID 87829722
6-[6-methoxy-7-[2-(7-methylidene-5-azaspiro[2.4]heptan-5-yl)ethoxy]quinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide
CID 46175442
3-[(6,7-dimethoxyquinolin-4-yl)amino]phenol;hydrochloride
CID 22646651
6,7-dimethoxy-N-(3-methoxyphenyl)quinolin-4-amine
CID 53264717
1-[2-[(6,7-dimethoxyquinolin-4-yl)amino]phenyl]ethanone
CID 53264744
2-cyclopropyl-1-[6-[7-[[1-(dimethylamino)cyclopropyl]methoxy]-6-methoxyquinolin-4-yl]oxynaphthalen-1-yl]ethanone
CID 157248452
6-[(6,7-dimethoxyquinazolin-4-yl)amino]-N-(4-fluorophenyl)naphthalene-1-carboxamide
CID 59813851

Frequently Asked Questions

What is the IUPAC name of 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide?
The IUPAC name of 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide (CID 25031636) is 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide.
What is the SMILES notation for 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide?
The canonical SMILES for 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide is CNC(=O)c1cccc2cc(Nc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12.
What is the InChIKey of 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide?
The InChIKey is MKPCPZGLIQMTQH-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H26N4O3/c1-28-25(31)19-5-3-4-16-12-17(6-7-18(16)19)30-21-8-11-29-22-14-24(23(32-2)13-20(21)22)33-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,31)(H,29,30).
What are the key properties of 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide?
6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide has a molecular weight of 442.52 g/mol, XLogP of 4.37, 7 rotatable bonds, 3 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]amino]-N-methylnaphthalene-1-carboxamide is sourced from PubChem (CID 25031636), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).