2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide

C25H25N5O2S2 — CID 25072168

About 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide

2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 25072168) has the molecular formula C25H25N5O2S2 and a molecular weight of 491.64 g/mol. Its IUPAC name is 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide
• PubChem CID: 25072168
• Molecular Formula: C25H25N5O2S2
• Molecular Weight: 491.64 g/mol
• Exact Mass: 491.14
• IUPAC Name: 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide
• SMILES: Cc1cccc(-c2sc(C)nc2C(=O)N2CSC[C@H]2CNC(=O)c2c(C)nc3ccccn23)c1
• InChI: InChI=1S/C25H25N5O2S2/c1-15-7-6-8-18(11-15)23-21(28-17(3)34-23)25(32)30-14-33-13-19(30)12-26-24(31)22-16(2)27-20-9-4-5-10-29(20)22/h4-11,19H,12-14H2,1-3H3,(H,26,31)/t19-/m1/s1
• InChIKey: KGSQYACFELREGZ-LJQANCHMSA-N
• XLogP: 4.33
• TPSA: 79.60 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 7
• Rotatable Bonds: 5
• Heavy Atoms: 34
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	491.64
LogP ≤ 5	4.33
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	7

Frequently Asked Questions

What is the IUPAC name of 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide?

The IUPAC name of 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide (CID 25072168) is 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide.

What is the SMILES notation for 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide?

The canonical SMILES for 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide is Cc1cccc(-c2sc(C)nc2C(=O)N2CSC[C@H]2CNC(=O)c2c(C)nc3ccccn23)c1.

What is the InChIKey of 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide?

The InChIKey is KGSQYACFELREGZ-LJQANCHMSA-N. The full InChI is InChI=1S/C25H25N5O2S2/c1-15-7-6-8-18(11-15)23-21(28-17(3)34-23)25(32)30-14-33-13-19(30)12-26-24(31)22-16(2)27-20-9-4-5-10-29(20)22/h4-11,19H,12-14H2,1-3H3,(H,26,31)/t19-/m1/s1.

What are the key properties of 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide?

2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 491.64 g/mol, XLogP of 4.33, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for 2-methyl-N-[[(4R)-3-[2-methyl-5-(3-methylphenyl)-1,3-thiazole-4-carbonyl]-1,3-thiazolidin-4-yl]methyl]imidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 25072168), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).