2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide

C12H10F2N2O2S — CID 33234261

IUPAC2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide
SMILESO=C(Cc1ccc(OC(F)F)cc1)Nc1nccs1
InChIInChI=1S/C12H10F2N2O2S/c13-11(14)18-9-3-1-8(2-4-9)7-10(17)16-12-15-5-6-19-12/h1-6,11H,7H2,(H,15,16,17)
InChIKeyIBBODLFUCGYARC-UHFFFAOYSA-N
MW284.29 g/mol
LogP2.93
Rot. Bonds5

About 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide

2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide (PubChem CID 33234261) has the molecular formula C12H10F2N2O2S and a molecular weight of 284.29 g/mol. Its IUPAC name is 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide.

Molecular Properties

Compound Name2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide
PubChem CID33234261
Molecular FormulaC12H10F2N2O2S
Molecular Weight284.29 g/mol
Exact Mass284.04
IUPAC Name2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide
SMILESO=C(Cc1ccc(OC(F)F)cc1)Nc1nccs1
InChIInChI=1S/C12H10F2N2O2S/c13-11(14)18-9-3-1-8(2-4-9)7-10(17)16-12-15-5-6-19-12/h1-6,11H,7H2,(H,15,16,17)
InChIKeyIBBODLFUCGYARC-UHFFFAOYSA-N
XLogP2.93
TPSA51.22 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds5
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500284.29
LogP ≤ 52.93
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

2-(4-methoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide
CID 770967
2-(4-bromophenyl)-N-(1,3-thiazol-2-yl)acetamide
CID 669868
3-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)prop-2-enamide
CID 3932279
2-[4-(difluoromethoxy)phenyl]-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide
CID 34110542
2-(4-pyridin-2-ylphenyl)-N-(1,3-thiazol-2-yl)acetamide
CID 172559309
2-(3,4-dimethoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide
CID 648788
N-(5-chloro-2-pyridinyl)-2-[4-(difluoromethoxy)phenyl]acetamide
CID 34136582
N-(4-acetamidophenyl)-2-[4-(difluoromethoxy)phenyl]acetamide
CID 35049094
2-[4-(difluoromethoxy)phenyl]-N-(4-methylphenyl)acetamide
CID 33142215
2-[4-(difluoromethoxy)phenyl]-N-[4-(piperidin-1-ylmethyl)-1,3-thiazol-2-yl]acetamide
CID 30183810
N-ethyl-2-(4-methoxyphenyl)-N-[2-oxo-2-(1,3-thiazol-2-ylamino)ethyl]acetamide
CID 814252
2-[4-(difluoromethoxy)phenyl]-N-(2-propan-2-ylpyrazol-3-yl)acetamide
CID 30183967

Frequently Asked Questions

What is the IUPAC name of 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide?
The IUPAC name of 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide (CID 33234261) is 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide.
What is the SMILES notation for 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide?
The canonical SMILES for 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide is O=C(Cc1ccc(OC(F)F)cc1)Nc1nccs1.
What is the InChIKey of 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide?
The InChIKey is IBBODLFUCGYARC-UHFFFAOYSA-N. The full InChI is InChI=1S/C12H10F2N2O2S/c13-11(14)18-9-3-1-8(2-4-9)7-10(17)16-12-15-5-6-19-12/h1-6,11H,7H2,(H,15,16,17).
What are the key properties of 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide?
2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide has a molecular weight of 284.29 g/mol, XLogP of 2.93, 5 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(difluoromethoxy)phenyl]-N-(1,3-thiazol-2-yl)acetamide is sourced from PubChem (CID 33234261), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).