[3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone

C36H32ClF3N6O — CID 58327789

About [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone

[3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone (PubChem CID 58327789) has the molecular formula C36H32ClF3N6O and a molecular weight of 657.14 g/mol. Its IUPAC name is [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone.

Molecular Properties

• Compound Name: [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone
• PubChem CID: 58327789
• Molecular Formula: C36H32ClF3N6O
• Molecular Weight: 657.14 g/mol
• Exact Mass: 656.23
• IUPAC Name: [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone
• SMILES: Cc1cc(N2CCN(C(=O)c3cccc(-c4cnc5c(c4)N(Cc4cc(Cl)ccc4C(F)(F)F)CCN5)c3)CC2)c2ccccc2n1
• InChI: InChI=1S/C36H32ClF3N6O/c1-23-17-32(29-7-2-3-8-31(29)43-23)44-13-15-45(16-14-44)35(47)25-6-4-5-24(18-25)26-20-33-34(42-21-26)41-11-12-46(33)22-27-19-28(37)9-10-30(27)36(38,39)40/h2-10,17-21H,11-16,22H2,1H3,(H,41,42)
• InChIKey: OMVPJUXMLZRSMB-UHFFFAOYSA-N
• XLogP: 7.67
• TPSA: 64.60 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 6
• Rotatable Bonds: 5
• Heavy Atoms: 47
• Complexity: —

Lipinski Rule of Five

2 violations

Rule	Value
MW ≤ 500	657.14
LogP ≤ 5	7.67
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	6

Frequently Asked Questions

What is the IUPAC name of [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone?

The IUPAC name of [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone (CID 58327789) is [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone.

What is the SMILES notation for [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone?

The canonical SMILES for [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone is Cc1cc(N2CCN(C(=O)c3cccc(-c4cnc5c(c4)N(Cc4cc(Cl)ccc4C(F)(F)F)CCN5)c3)CC2)c2ccccc2n1.

What is the InChIKey of [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone?

The InChIKey is OMVPJUXMLZRSMB-UHFFFAOYSA-N. The full InChI is InChI=1S/C36H32ClF3N6O/c1-23-17-32(29-7-2-3-8-31(29)43-23)44-13-15-45(16-14-44)35(47)25-6-4-5-24(18-25)26-20-33-34(42-21-26)41-11-12-46(33)22-27-19-28(37)9-10-30(27)36(38,39)40/h2-10,17-21H,11-16,22H2,1H3,(H,41,42).

What are the key properties of [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone?

[3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone has a molecular weight of 657.14 g/mol, XLogP of 7.67, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.

Where does this data come from?

All data for [3-[1-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-7-yl]phenyl]-[4-(2-methylquinolin-4-yl)piperazin-1-yl]methanone is sourced from PubChem (CID 58327789), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).