8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide

C19H18FN5O — CID 58495788

IUPAC8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide
SMILESNC(=O)c1ccc2cncc(N3CCN(c4ccc(F)cc4)CC3)c2n1
InChIInChI=1S/C19H18FN5O/c20-14-2-4-15(5-3-14)24-7-9-25(10-8-24)17-12-22-11-13-1-6-16(19(21)26)23-18(13)17/h1-6,11-12H,7-10H2,(H2,21,26)
InChIKeyCEJIJDAGKPJILT-UHFFFAOYSA-N
MW351.39 g/mol
LogP2.19
Rot. Bonds3

About 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide

8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide (PubChem CID 58495788) has the molecular formula C19H18FN5O and a molecular weight of 351.39 g/mol. Its IUPAC name is 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide.

Molecular Properties

Compound Name8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide
PubChem CID58495788
Molecular FormulaC19H18FN5O
Molecular Weight351.39 g/mol
Exact Mass351.15
IUPAC Name8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide
SMILESNC(=O)c1ccc2cncc(N3CCN(c4ccc(F)cc4)CC3)c2n1
InChIInChI=1S/C19H18FN5O/c20-14-2-4-15(5-3-14)24-7-9-25(10-8-24)17-12-22-11-13-1-6-16(19(21)26)23-18(13)17/h1-6,11-12H,7-10H2,(H2,21,26)
InChIKeyCEJIJDAGKPJILT-UHFFFAOYSA-N
XLogP2.19
TPSA75.35 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500351.39
LogP ≤ 52.19
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

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Related Compounds

8-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide
CID 58495753
8-[3-(difluoromethoxymethyl)piperidin-1-yl]-1,6-naphthyridine-2-carboxamide
CID 58495812
4-[4-(4-acetylphenyl)piperazin-1-yl]isoquinoline-6-carboxamide
CID 58495716
3-amino-4-[4-(4-fluorophenyl)piperazin-1-yl]thieno[2,3-b]pyridine-2-carboxamide
CID 69364640
[4-(4-fluorophenyl)piperazin-1-yl]-(6-methyl-2-pyridinyl)methanone
CID 110697414
[6-[4-(4-fluorophenyl)piperazin-1-yl]pyridazin-3-yl]-pyrrolidin-1-ylmethanone
CID 109111932
1-[4-(chloromethyl)-3-pyridinyl]-4-(4-fluorophenyl)piperazine
CID 105067256
5-[4-(4-fluorophenyl)piperazin-1-yl]-N-propan-2-ylpyridine-2-carboxamide
CID 109179488
[5-(4-fluoroanilino)-2-pyridinyl]-[4-(4-fluorophenyl)piperazin-1-yl]methanone
CID 109193490
N-cyclopentyl-5-[4-(4-fluorophenyl)piperazin-1-yl]pyridine-2-carboxamide
CID 109182203
5-[4-(4-fluorophenyl)piperazin-1-yl]-N-(5-methyl-1,2-oxazol-3-yl)pyridine-3-carboxamide
CID 109237631
8-[4-(aminomethyl)phenyl]-1,6-naphthyridine-2-carboxamide
CID 90178332

Frequently Asked Questions

What is the IUPAC name of 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide?
The IUPAC name of 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide (CID 58495788) is 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide.
What is the SMILES notation for 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide?
The canonical SMILES for 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide is NC(=O)c1ccc2cncc(N3CCN(c4ccc(F)cc4)CC3)c2n1.
What is the InChIKey of 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide?
The InChIKey is CEJIJDAGKPJILT-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H18FN5O/c20-14-2-4-15(5-3-14)24-7-9-25(10-8-24)17-12-22-11-13-1-6-16(19(21)26)23-18(13)17/h1-6,11-12H,7-10H2,(H2,21,26).
What are the key properties of 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide?
8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide has a molecular weight of 351.39 g/mol, XLogP of 2.19, 3 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 8-[4-(4-fluorophenyl)piperazin-1-yl]-1,6-naphthyridine-2-carboxamide is sourced from PubChem (CID 58495788), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).