8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

C18H15FN4O — CID 71657853

IUPAC8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide
SMILESNc1ncc(C(=O)NC2CC2)c2ccc(-c3cccc(F)c3)nc12
InChIInChI=1S/C18H15FN4O/c19-11-3-1-2-10(8-11)15-7-6-13-14(18(24)22-12-4-5-12)9-21-17(20)16(13)23-15/h1-3,6-9,12H,4-5H2,(H2,20,21)(H,22,24)
InChIKeyXWLOYAAKIFUZDU-UHFFFAOYSA-N
MW322.34 g/mol
LogP2.91
Rot. Bonds3

About 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide (PubChem CID 71657853) has the molecular formula C18H15FN4O and a molecular weight of 322.34 g/mol. Its IUPAC name is 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide.

Molecular Properties

Compound Name8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide
PubChem CID71657853
Molecular FormulaC18H15FN4O
Molecular Weight322.34 g/mol
Exact Mass322.12
IUPAC Name8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide
SMILESNc1ncc(C(=O)NC2CC2)c2ccc(-c3cccc(F)c3)nc12
InChIInChI=1S/C18H15FN4O/c19-11-3-1-2-10(8-11)15-7-6-13-14(18(24)22-12-4-5-12)9-21-17(20)16(13)23-15/h1-3,6-9,12H,4-5H2,(H2,20,21)(H,22,24)
InChIKeyXWLOYAAKIFUZDU-UHFFFAOYSA-N
XLogP2.91
TPSA80.90 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500322.34
LogP ≤ 52.91
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

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Related Compounds

3-Amino-N-(2'-Amino-6'-Methyl[4,4'-Bipyridin]-3-Yl)-6-(2-Fluorophenyl)pyridine-2-Carboxamide
CID 68161871
8-Amino-N-[1-(Cyclopropylcarbonyl)azetidin-3-Yl]-2-(3-Fluorophenyl)-1,7-Naphthyridine-5-Carboxamide
CID 89730041
N-(6-methyl-2-pyridinyl)-6-quinoxalinecarboxamide
CID 829895
N-(6-{2-[2-(2-Amino-3-{3-[(3,3-Dimethylbutyl)amino]-3-Oxopropyl}quinolin-6-Yl)phenyl]ethyl}pyridin-3-Yl)-4-Fluorobenzamide
CID 118797905
2-ethyl-9-methyl-13-(2-phenylethyl)-5-(1H-pyrrol-2-yl)-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-10-one
CID 470743
6-{[(1R)-2-methyl-1-(trifluoromethyl)propyl]amino}pyrido[4,3-c]-1,6-naphthyridin-1(2H)-one
CID 25096016
3-amino-N-[4-(2-amino-4-pyridinyl)-3-pyridinyl]-6-(2-fluorophenyl)pyridine-2-carboxamide
CID 68161034
3-amino-N-[4-(2-amino-6-methyl-4-pyridinyl)-3-pyridinyl]-6-(2,6-difluorophenyl)pyridine-2-carboxamide
CID 68163204
8-amino-2-(3-fluorophenyl)-N-(1-propanoylazetidin-3-yl)-1,7-naphthyridine-5-carboxamide
CID 89730033
8-amino-2-(3-fluorophenyl)-N-(1-(methylcarbamoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide
CID 89730039
8-amino-2-(3-fluorophenyl)-N-(trans-3-hydroxycyclobutyl)-1,7-naphthyridine-5-carboxamide
CID 89730047
Nevirapin 4-substituted deriv. 4z
CID 464545

Frequently Asked Questions

What is the IUPAC name of 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide?
The IUPAC name of 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide (CID 71657853) is 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide.
What is the SMILES notation for 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide?
The canonical SMILES for 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide is Nc1ncc(C(=O)NC2CC2)c2ccc(-c3cccc(F)c3)nc12.
What is the InChIKey of 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide?
The InChIKey is XWLOYAAKIFUZDU-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15FN4O/c19-11-3-1-2-10(8-11)15-7-6-13-14(18(24)22-12-4-5-12)9-21-17(20)16(13)23-15/h1-3,6-9,12H,4-5H2,(H2,20,21)(H,22,24).
What are the key properties of 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide?
8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide has a molecular weight of 322.34 g/mol, XLogP of 2.91, 3 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide is sourced from PubChem (CID 71657853), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).