N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide

C16H16F2N4O2 — CID 71799286

IUPACN-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide
SMILESO=C(Nc1c(F)cccc1F)N1CCC(Oc2cnccn2)CC1
InChIInChI=1S/C16H16F2N4O2/c17-12-2-1-3-13(18)15(12)21-16(23)22-8-4-11(5-9-22)24-14-10-19-6-7-20-14/h1-3,6-7,10-11H,4-5,8-9H2,(H,21,23)
InChIKeyQKXOHIUUNQWUTC-UHFFFAOYSA-N
MW334.33 g/mol
LogP2.83
Rot. Bonds3

About N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide

N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide (PubChem CID 71799286) has the molecular formula C16H16F2N4O2 and a molecular weight of 334.33 g/mol. Its IUPAC name is N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide.

Molecular Properties

Compound NameN-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide
PubChem CID71799286
Molecular FormulaC16H16F2N4O2
Molecular Weight334.33 g/mol
Exact Mass334.12
IUPAC NameN-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide
SMILESO=C(Nc1c(F)cccc1F)N1CCC(Oc2cnccn2)CC1
InChIInChI=1S/C16H16F2N4O2/c17-12-2-1-3-13(18)15(12)21-16(23)22-8-4-11(5-9-22)24-14-10-19-6-7-20-14/h1-3,6-7,10-11H,4-5,8-9H2,(H,21,23)
InChIKeyQKXOHIUUNQWUTC-UHFFFAOYSA-N
XLogP2.83
TPSA67.35 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500334.33
LogP ≤ 52.83
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

N-(2,6-difluorophenyl)-4-pyridazin-3-yloxypiperidine-1-carboxamide
CID 90559382
N-(2-methoxyphenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide
CID 90559095
N-(4-chlorophenyl)-3-pyrazin-2-yloxypyrrolidine-1-carboxamide
CID 90636300
(2-chloro-6-fluorophenyl)-[(3R)-3-pyrazin-2-yloxypyrrolidin-1-yl]methanone
CID 100753127
(3S)-3-pyrazin-2-yloxy-N-thiophen-2-ylpyrrolidine-1-carboxamide
CID 100754062
N-[3-(oxolan-3-yl)phenyl]-4-pyrazin-2-yloxypiperidine-1-carboxamide
CID 166315481
(4-pyrazin-2-yloxypiperidin-1-yl)-pyridin-2-ylmethanone
CID 71799257
2-(4-fluorophenyl)-1-(4-pyrazin-2-yloxypiperidin-1-yl)ethanone
CID 90559036
3-pyrazin-2-yloxypyrrolidine-1-carboxylic acid
CID 134496966
(2-chloro-4-fluorophenyl)-(4-pyrazin-2-yloxypiperidin-1-yl)methanone
CID 90559064
N-(2,6-difluorophenyl)-3-[[4-(trifluoromethyl)-2-pyridinyl]oxy]azetidine-1-carboxamide
CID 122251579
3-chloro-1-(4-pyrazin-2-yloxypiperidin-1-yl)propan-1-one
CID 90558978

Frequently Asked Questions

What is the IUPAC name of N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide?
The IUPAC name of N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide (CID 71799286) is N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide.
What is the SMILES notation for N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide?
The canonical SMILES for N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide is O=C(Nc1c(F)cccc1F)N1CCC(Oc2cnccn2)CC1.
What is the InChIKey of N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide?
The InChIKey is QKXOHIUUNQWUTC-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H16F2N4O2/c17-12-2-1-3-13(18)15(12)21-16(23)22-8-4-11(5-9-22)24-14-10-19-6-7-20-14/h1-3,6-7,10-11H,4-5,8-9H2,(H,21,23).
What are the key properties of N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide?
N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide has a molecular weight of 334.33 g/mol, XLogP of 2.83, 3 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-(2,6-difluorophenyl)-4-pyrazin-2-yloxypiperidine-1-carboxamide is sourced from PubChem (CID 71799286), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).