(3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide

C13H16F2N2O2 — CID 81123871

IUPAC(3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide
SMILESO=C(Nc1ccc(OC(F)F)cc1)[C@@H]1CCCNC1
InChIInChI=1S/C13H16F2N2O2/c14-13(15)19-11-5-3-10(4-6-11)17-12(18)9-2-1-7-16-8-9/h3-6,9,13,16H,1-2,7-8H2,(H,17,18)/t9-/m1/s1
InChIKeyHKGRGZHNKGZVFR-SECBINFHSA-N
MW270.28 g/mol
LogP2.23
Rot. Bonds4

About (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide

(3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide (PubChem CID 81123871) has the molecular formula C13H16F2N2O2 and a molecular weight of 270.28 g/mol. Its IUPAC name is (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide.

Molecular Properties

Compound Name(3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide
PubChem CID81123871
Molecular FormulaC13H16F2N2O2
Molecular Weight270.28 g/mol
Exact Mass270.12
IUPAC Name(3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide
SMILESO=C(Nc1ccc(OC(F)F)cc1)[C@@H]1CCCNC1
InChIInChI=1S/C13H16F2N2O2/c14-13(15)19-11-5-3-10(4-6-11)17-12(18)9-2-1-7-16-8-9/h3-6,9,13,16H,1-2,7-8H2,(H,17,18)/t9-/m1/s1
InChIKeyHKGRGZHNKGZVFR-SECBINFHSA-N
XLogP2.23
TPSA50.36 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds4
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500270.28
LogP ≤ 52.23
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[3-chloro-4-(difluoromethoxy)phenyl]piperidine-3-carboxamide
CID 61260908
(3S)-N-[2-[4-(difluoromethoxy)phenyl]ethyl]piperidine-3-carboxamide
CID 81133526
N-[4-(difluoromethylsulfanyl)phenyl]piperidine-3-carboxamide
CID 43698982
N-[4-[4-(difluoromethoxy)phenyl]-5-methyl-1,3-thiazol-2-yl]piperidine-3-carboxamide
CID 119273428
(3R)-N-[2-(difluoromethoxy)-5-methoxyphenyl]piperidine-3-carboxamide
CID 81119085
N-[4-(propan-2-ylcarbamoyl)phenyl]piperidine-3-carboxamide
CID 60927369
methyl 2-[4-[[(3S)-piperidine-3-carbonyl]amino]phenoxy]acetate
CID 81118246
3-amino-N-[4-(difluoromethoxy)phenyl]cyclohexane-1-carboxamide;hydrochloride
CID 119676533
N-[4-(3-fluorophenoxy)phenyl]piperidine-3-carboxamide;hydrochloride
CID 119299176
(2S,4S)-N-[4-(difluoromethoxy)phenyl]-2-methylpiperidine-4-carboxamide;hydrochloride
CID 120616787
propan-2-yl 4-(piperidine-3-carbonylamino)benzoate
CID 43702839
(3S)-N-[4-(dimethylamino)phenyl]piperidine-3-carboxamide
CID 28807397

Frequently Asked Questions

What is the IUPAC name of (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide?
The IUPAC name of (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide (CID 81123871) is (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide.
What is the SMILES notation for (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide?
The canonical SMILES for (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide is O=C(Nc1ccc(OC(F)F)cc1)[C@@H]1CCCNC1.
What is the InChIKey of (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide?
The InChIKey is HKGRGZHNKGZVFR-SECBINFHSA-N. The full InChI is InChI=1S/C13H16F2N2O2/c14-13(15)19-11-5-3-10(4-6-11)17-12(18)9-2-1-7-16-8-9/h3-6,9,13,16H,1-2,7-8H2,(H,17,18)/t9-/m1/s1.
What are the key properties of (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide?
(3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide has a molecular weight of 270.28 g/mol, XLogP of 2.23, 4 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (3R)-N-[4-(difluoromethoxy)phenyl]piperidine-3-carboxamide is sourced from PubChem (CID 81123871), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).