2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide

C18H18F3N3O3 — CID 88859476

IUPAC2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide
SMILESO=C(Nc1ccc(-n2ccc(OC3CCNCC3)cc2=O)cc1)C(F)(F)F
InChIInChI=1S/C18H18F3N3O3/c19-18(20,21)17(26)23-12-1-3-13(4-2-12)24-10-7-15(11-16(24)25)27-14-5-8-22-9-6-14/h1-4,7,10-11,14,22H,5-6,8-9H2,(H,23,26)
InChIKeyFLMHYUWVHOVNOP-UHFFFAOYSA-N
MW381.35 g/mol
LogP2.47
Rot. Bonds4

About 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide

2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide (PubChem CID 88859476) has the molecular formula C18H18F3N3O3 and a molecular weight of 381.35 g/mol. Its IUPAC name is 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide.

Molecular Properties

Compound Name2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide
PubChem CID88859476
Molecular FormulaC18H18F3N3O3
Molecular Weight381.35 g/mol
Exact Mass381.13
IUPAC Name2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide
SMILESO=C(Nc1ccc(-n2ccc(OC3CCNCC3)cc2=O)cc1)C(F)(F)F
InChIInChI=1S/C18H18F3N3O3/c19-18(20,21)17(26)23-12-1-3-13(4-2-12)24-10-7-15(11-16(24)25)27-14-5-8-22-9-6-14/h1-4,7,10-11,14,22H,5-6,8-9H2,(H,23,26)
InChIKeyFLMHYUWVHOVNOP-UHFFFAOYSA-N
XLogP2.47
TPSA72.36 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500381.35
LogP ≤ 52.47
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Analyze 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide with MolForge

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Related Compounds

propan-2-yl 4-[[2-oxo-1-[4-[(2,2,2-trifluoroacetyl)amino]phenyl]-4-pyridinyl]oxy]piperidine-1-carboxylate
CID 57468364
2,2,2-trifluoro-N-[4-[(2,2,2-trifluoroacetyl)amino]phenyl]acetamide
CID 5013683
4-[[1-(4-methoxyphenyl)-2-oxo-4-pyridinyl]oxy]piperidine-1-carboxylic acid
CID 57468346
2,2,2-trifluoro-N-[4-(5-methyl-3-oxo-1H-pyrazol-2-yl)phenyl]acetamide
CID 54194788
2-piperidin-4-yloxyfluoren-9-one;2,2,2-trifluoroacetic acid
CID 67164914
N-(4-piperidin-4-yloxyphenyl)-6-(trifluoromethyl)pyridine-3-carboxamide;2,2,2-trifluoroacetic acid
CID 172895263
2,2,2-trifluoro-N-[4-(piperidin-4-ylmethyl)phenyl]acetamide;2,2,2-trifluoro-N-[4-(pyridin-4-ylmethyl)phenyl]acetamide
CID 90012791
4-(4-chloro-3-pyrazol-1-ylphenoxy)piperidine;2,2,2-trifluoroacetic acid
CID 155142012
N-[4-[(3S)-pyrrolidin-3-yl]oxyphenyl]acetamide
CID 86322818
pyrrolidin-3-yl N-[4-(trifluoromethoxy)phenyl]carbamate
CID 115565228
4-methyl-N-(4-piperidin-4-yloxyphenyl)pentanamide
CID 23366912
(2,2,2-trifluoroacetyl) 4-piperidin-4-yloxybenzoate
CID 123933976

Frequently Asked Questions

What is the IUPAC name of 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide?
The IUPAC name of 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide (CID 88859476) is 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide.
What is the SMILES notation for 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide?
The canonical SMILES for 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide is O=C(Nc1ccc(-n2ccc(OC3CCNCC3)cc2=O)cc1)C(F)(F)F.
What is the InChIKey of 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide?
The InChIKey is FLMHYUWVHOVNOP-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H18F3N3O3/c19-18(20,21)17(26)23-12-1-3-13(4-2-12)24-10-7-15(11-16(24)25)27-14-5-8-22-9-6-14/h1-4,7,10-11,14,22H,5-6,8-9H2,(H,23,26).
What are the key properties of 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide?
2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide has a molecular weight of 381.35 g/mol, XLogP of 2.47, 4 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2,2,2-trifluoro-N-[4-(2-oxo-4-piperidin-4-yloxy-1-pyridinyl)phenyl]acetamide is sourced from PubChem (CID 88859476), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).