Transmembrane protein 223 (TMEM223)

About Transmembrane protein 223

Transmembrane protein 223 (TMEM223) is a protein from Homo sapiens identified by UniProt accession A0PJW6, 202 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Transmembrane protein 223
UniProt accession	A0PJW6
Gene	TMEM223
Organism	Homo sapiens
Length	202 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

mean reticulocyte volume · score 0.10
mean platelet volume · score 0.03
breast cancer · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A0PJW6-F1	alphafold	PREDICTED	73.75	—

Amino-acid sequence (202 residues)

MAAPWRRWPT GLLAVLRPLL TCRPLQGTTL QRDVLLFEHD RGRFFTILGL FCAGQGVFWA SMAVAAVSRP PVPVQPLDAE VPNRGPFDLR SALWRYGLAV GCGAIGALVL GAGLLFSLRS VRSVVLRAGG QQVTLTTHAP FGLGAHFTVP LKQVSCMAHR GEVPAMLPLK VKGRRFYFLL DKTGHFPNTK LFDNTVGAYR SL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards