Death-associated protein-like 1 (DAPL1)

About Death-associated protein-like 1

Death-associated protein-like 1 (DAPL1) is a protein from Homo sapiens identified by UniProt accession A0PJW8, 107 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	Death-associated protein-like 1
UniProt accession	A0PJW8
Gene	DAPL1
Organism	Homo sapiens
Length	107 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

creatinine measurement · score 0.39
neurodegenerative disease · score 0.32
platelet crit · score 0.30
visceral adipose tissue measurement · score 0.28
cystatin C measurement · score 0.28
systolic blood pressure · score 0.10
neuroticism measurement · score 0.07
retinitis pigmentosa · score 0.07
choroidal dystrophy, central areolar, 1 · score 0.06
age-related macular degeneration · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A0PJW8-F1	alphafold	PREDICTED	68.18	—

Amino-acid sequence (107 residues)

MANEVQDLLS PRKGGHPPAV KAGGMRISKK QEIGTLERHT KKTGFEKTSA IANVAKIQTL DALNDALEKL NYKFPATVHM AHQKPTPALE KVVPLKRIYI IQQPRKC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards