About Transmembrane protein 82
Transmembrane protein 82 (TMEM82) is a protein
from Homo sapiens identified by UniProt accession
A0PJX8, 343 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Transmembrane protein 82 |
|---|
| UniProt accession | A0PJX8 |
|---|
| Gene | TMEM82 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 343 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- Barrett's esophagus · score 0.05
- metabolite measurement · score 0.04
- hepatocellular carcinoma · score 0.03
- pulse pressure measurement · score 0.03
- systolic blood pressure · score 0.03
- heel bone mineral density · score 0.03
- non-small cell lung carcinoma · score 0.02
- ulcerative colitis · score 0.01
- Crohn's disease · score 0.01
- colorectal carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A0PJX8-F1 | alphafold | PREDICTED | 77.92 | — |
Amino-acid sequence (343 residues)
MFSLPSLPSW LPGLPSLEWG SSLLDSLLQG LIGALGVLVL NSLLKVYFFV GCANDPQRRP EKERLRAQWA SLETVHLAGL ALFLTVVGSR VAALVVLEFS LRAVSTLLSL GKGSQGAAER LQLYLLCQYS LGCGLTCGLS FLQEGAPHRT LNLLLSLGLA TLLGLGARRL HRHVCRLYEL HSSQRYCGVC LGLLAHAHGL PQLLGRALAI AFAVGDLAAV ALINQDFLTT SEAMRFWTPL TICYTLLVIY MQEEQRQHPG LQSQVQTVLV RMGGLFVLLL TVGRWLDLLG ILVSLLGELW CLVGVRTLLD LCQIQDFPSQ RPPVSTPSQP LPSAPQSQSS APS
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