Myelin-associated neurite-outgrowth inhibitor…

About Myelin-associated neurite-outgrowth inhibitor

Myelin-associated neurite-outgrowth inhibitor (FAM168B) is a protein from Homo sapiens identified by UniProt accession A1KXE4, 195 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Myelin-associated neurite-outgrowth inhibitor
UniProt accession	A1KXE4
Gene	FAM168B
Organism	Homo sapiens
Length	195 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

myoepithelial tumor · score 0.11
congenital left-sided heart lesions · score 0.03
protein measurement · score 0.03
neurodegenerative disease · score 0.01
infection · score 0.01
infect · score 0.01
Salmonella Infections · score 0.01
Alzheimer disease · score 0.00
multiple myeloma · score 0.00
Parkinson disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1KXE4-F1	alphafold	PREDICTED	50.24	—

Amino-acid sequence (195 residues)

MNPVYSPGSS GVPYANAKGI GYPAGFPMGY AAAAPAYSPN MYPGANPTFQ TGYTPGTPYK VSCSPTSGAV PPYSSSPNPY QTAVYPVRSA YPQQSPYAQQ GTYYTQPLYA APPHVIHHTT VVQPNGMPAT VYPAPIPPPR GNGVTMGMVA GTTMAMSAGT LLTAHSPTPV APHPVTVPTY RAPGTPTYSY VPPQW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Myelin-associated neurite-outgrowth inhibitor (FAM168B)