About Synaptonemal complex central element protein 3
Synaptonemal complex central element protein 3 (SYCE3) is a protein
from Homo sapiens identified by UniProt accession
A1L190, 88 residues long.
MolForge cross-references it against 0 known binders and
146 disease associations.
Target properties
| Protein name | Synaptonemal complex central element protein 3 |
|---|
| UniProt accession | A1L190 |
|---|
| Gene | SYCE3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 88 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (146)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- mean corpuscular volume · score 0.24
- mean corpuscular hemoglobin concentration · score 0.19
- mean corpuscular hemoglobin · score 0.19
- azoospermia · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- partial chromosome Y deletion · score 0.07
- primary ovarian insufficiency · score 0.07
- spermatogenic failures 50 · score 0.06
- spinocerebellar ataxia type 32 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A1L190-F1 | alphafold | PREDICTED | 93.58 | — |
Amino-acid sequence (88 residues)
MDDADPEERN YDNMLKMLSD LNKDLEKLLE EMEKISVQAT WMAYDMVVMR TNPTLAESMR RLEDAFVNCK EEMEKNWQEL LHETKQRL
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