PLAC8-like protein 1 (PLAC8L1)

About PLAC8-like protein 1

PLAC8-like protein 1 (PLAC8L1) is a protein from Homo sapiens identified by UniProt accession A1L4L8, 177 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	PLAC8-like protein 1
UniProt accession	A1L4L8
Gene	PLAC8L1
Organism	Homo sapiens
Length	177 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurofibrillary tangles measurement · score 0.20
electrocardiography · score 0.17
mathematical ability · score 0.13
self reported educational attainment · score 0.12
Alzheimer disease · score 0.11
age at onset · score 0.11
Red cell distribution width · score 0.07
prostate carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1L4L8-F1	alphafold	PREDICTED	72.64	—

Amino-acid sequence (177 residues)

MNWFGSNFFR CPEDLSLLNI YSPLLSHMSS EDEHFISNLR GHVPASAVVK QPVRGASGRT TITAIVQTGG GWSTGLFSVC RDRRICFCGL FCPMCLECDI ARHYGECLCW PLLPGSTFAL RIGTRERHKI QGTLCEDWLA VHCCWAFSIC QVARELKMRT SQVYEICAVP MTKDTLV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards