Serine-rich and transmembrane domain-containing…

About Serine-rich and transmembrane domain-containing protein 1

Serine-rich and transmembrane domain-containing protein 1 (SERTM1) is a protein from Homo sapiens identified by UniProt accession A2A2V5, 107 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Serine-rich and transmembrane domain-containing protein 1
UniProt accession	A2A2V5
Gene	SERTM1
Organism	Homo sapiens
Length	107 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

protein measurement · score 0.24
ovarian carcinoma · score 0.05
central nervous system cancer · score 0.05
non-small cell lung carcinoma · score 0.04
glioblastoma multiforme · score 0.03
medulloblastoma · score 0.03
astrocytoma · score 0.02
psoriasis · score 0.02
smoking status measurement · score 0.02
oligodendroglioma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A2A2V5-F1	alphafold	PREDICTED	63.21	—

Amino-acid sequence (107 residues)

MSEPDTSSGF SGSVENGTFL ELFPTSLSTS VDPSSGHLSN VYIYVSIFLS LLAFLLLLLI IALQRLKNII SSSSSYPEYP SDAGSSFTNL EVCSISSQRS TFSNLSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Serine-rich and transmembrane domain-containing protein 1 (SERTM1)