Melanoma-associated antigen B16 (MAGEB16)

About Melanoma-associated antigen B16

Melanoma-associated antigen B16 (MAGEB16) is a protein from Homo sapiens identified by UniProt accession A2A368, 324 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Melanoma-associated antigen B16
UniProt accession	A2A368
Gene	MAGEB16
Organism	Homo sapiens
Length	324 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.03
neoplasm · score 0.01
cancer · score 0.00
chondrosarcoma · score 0.00
Neurodevelopmental disorder · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A2A368-F1	alphafold	PREDICTED	74.15	—

Amino-acid sequence (324 residues)

MSQDQESPRC THDQHLQTFS ETQSLEVAQV SKALEKTLLS SSHPLVPGKL KEAPAAKAES PLEVPQSFCS SSIAVTTTSS SESDEASSNQ EEEDSPSSSE DTSDPRNVPA DALDQKVAFL VNFMLHKCQM KKPITKADML KIIIKDDESH FSEILLRASE HLEMIFGLDV VEVDPTTHCY GLFIKLGLTY DGMLSGEKGV PKTGLLIIVL GVIFMKGNRA TEEEVWEVLN LTGVYSGKKH FIFGEPRMLI TKDFVKEKYL EYQQVANSDP ARYEFLWGPR AKAETSKMKV LEFVAKVHGS YPHSFPSQYA EALKEEEERA RARI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards