Transmembrane protein 213 (TMEM213)

About Transmembrane protein 213

Transmembrane protein 213 (TMEM213) is a protein from Homo sapiens identified by UniProt accession A2RRL7, 107 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Transmembrane protein 213
UniProt accession	A2RRL7
Gene	TMEM213
Organism	Homo sapiens
Length	107 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

age-related hearing impairment · score 0.34
diet measurement · score 0.23
hearing loss · score 0.23
PHF-tau measurement · score 0.22
genetic disorder · score 0.18
autosomal recessive distal renal tubular acidosis · score 0.18
Retinal dystrophy · score 0.15
high density lipoprotein cholesterol measurement · score 0.12
sleep duration · score 0.12
clear cell renal carcinoma · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A2RRL7-F1	alphafold	PREDICTED	68.44	—

Amino-acid sequence (107 residues)

MQRLPAATRA TLILSLAFAS LHSACSAEAS SSNSSSLTAH HPDPGTLEQC LNVDFCPQAA RCCRTGVDEY GWIAAAVGWS LWFLTLILLC VDKLMKLTPD EPKDLQA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards