Protein SPMIP7 (SPMIP7)

About Protein SPMIP7

Protein SPMIP7 (SPMIP7) is a protein from Homo sapiens identified by UniProt accession A4D263, 438 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.

Target properties

Protein name	Protein SPMIP7
UniProt accession	A4D263
Gene	SPMIP7
Organism	Homo sapiens
Length	438 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (130)

Diseases linked to this target (Open Targets).

monocyte percentage of leukocytes · score 0.41
eosinophil count · score 0.36
basal cell carcinoma · score 0.27
Crohn's disease · score 0.27
inflammatory bowel disease · score 0.26
eosinophil percentage of leukocytes · score 0.25
keratinocyte carcinoma · score 0.22
lymphocyte:monocyte ratio · score 0.21
neutrophil percentage of granulocytes · score 0.20
physical activity measurement · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A4D263-F1	alphafold	PREDICTED	55.96	—

Amino-acid sequence (438 residues)

MDVEIQDTPG KISISKRSIL SGTVENIDYP HYCDLLRKMN MPFVKGLENR HNYGRFEKKC NPAFLKFHPY PPSVLPDYHL HDPYPPPYGP HYPLFPLRDD VTLGDSCSGF MSPGGDADLN PGIGRTIPTL VDFSDVKPQH RVPRPDTGFQ TTIKRQKILS EELQQNRRWN SREVPDISIR ARLGGWTSPL KVTPLQPHHE GRSLSHIFTF DEEATCTDEG EPLVQTNKKC NAKDSFYKSS TQKAYEDVPW DKMLPPKLVP EETTLEKTAD PISQCFTLKR YKGVPAITQM VGELWDRFQT RSFLAPVKPI NFVSSSSRSK YIPLYTGHVQ STNADDVDNP LGDIASLAKQ RYSKPLYTNT SRAANIPGYT GKVHFTATHP ANSNIPSTTP SPDSELHRVF QKEMAVDLFR HQAPLSRLVT TVRPYNPFNK KDKETIDY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards