Plasmanylethanolamine desaturase 1 (PEDS1)

About Plasmanylethanolamine desaturase 1

Plasmanylethanolamine desaturase 1 (PEDS1) is a protein from Homo sapiens identified by UniProt accession A5PLL7, 270 residues long. MolForge cross-references it against 0 known binders and 228 disease associations.

Target properties

Protein name	Plasmanylethanolamine desaturase 1
UniProt accession	A5PLL7
Gene	PEDS1
Organism	Homo sapiens
Length	270 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (228)

Diseases linked to this target (Open Targets).

monocyte count · score 0.22
monocyte percentage of leukocytes · score 0.20
granulocyte percentage of myeloid white cells · score 0.16
testosterone measurement · score 0.14
lymphocyte:monocyte ratio · score 0.13
breast carcinoma · score 0.12
optic cup area measurement · score 0.12
hair colour measurement · score 0.12
gut microbiome measurement · score 0.11
inflammatory bowel disease · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A5PLL7-F1	alphafold	PREDICTED	90.52	—

Amino-acid sequence (270 residues)

MAGAENWPGQ QLELDEDEAS CCRWGAQHAG ARELAALYSP GKRLQEWCSV ILCFSLIAHN LVHLLLLARW EDTPLVILGV VAGALIADFL SGLVHWGADT WGSVELPIVG KAFIRPFREH HIDPTAITRH DFIETNGDNC LVTLLPLLNM AYKFRTHSPE ALEQLYPWEC FVFCLIIFGT FTNQIHKWSH TYFGLPRWVT LLQDWHVILP RKHHRIHHVS PHETYFCITT GWLNYPLEKI GFWRRLEDLI QGLTGEKPRA DDMKWAQKIK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards