About Glutaredoxin-like protein C5orf63
Glutaredoxin-like protein C5orf63 (C5orf63) is a protein
from Homo sapiens identified by UniProt accession
A6NC05, 138 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Glutaredoxin-like protein C5orf63 |
|---|
| UniProt accession | A6NC05 |
|---|
| Gene | C5orf63 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 138 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.24
- FEV/FVC ratio · score 0.21
- cortical thickness · score 0.15
- optic disc size measurement · score 0.14
- serum metabolite measurement · score 0.09
- Immature Reticulocyte Fraction Measurement · score 0.04
- Down syndrome · score 0.03
- Helicobacter pylori infectious disease · score 0.03
- creatinine measurement · score 0.03
- reticulocyte measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NC05-F1 | alphafold | PREDICTED | 45.24 | — |
Amino-acid sequence (138 residues)
MLWFQGNSMQ LARSSFGLFL RNCSASKTTL PVLTLFTKDP CPLCDEAKEV LKPYENRQPY KDQKLPGTRR RRSPSSPSHP HMASQSGKRY NLTLNQVLSF DYDMGLDAPK TISSDCGAFY CLRMFKSPDM TCCFYPKQ
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