About Transmembrane protein 247
Transmembrane protein 247 (TMEM247) is a protein
from Homo sapiens identified by UniProt accession
A6NEH6, 219 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Transmembrane protein 247 |
|---|
| UniProt accession | A6NEH6 |
|---|
| Gene | TMEM247 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 219 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.32
- fat body mass · score 0.24
- whole body water mass · score 0.24
- base metabolic rate measurement · score 0.23
- excessive daytime sleepiness measurement · score 0.22
- serum alanine aminotransferase measurement · score 0.15
- Abnormality of refraction · score 0.09
- hemoglobin measurement · score 0.09
- sitting height measurement · score 0.07
- hematocrit · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NEH6-F1 | alphafold | PREDICTED | 65.95 | — |
Amino-acid sequence (219 residues)
MAAEDREMME ARGAGESCPT FPKMVPGDSK SEGKPRAYLE AESQKPDSSY DYLEEMEACE DGGCQGPLKS LSPKSCRATK GQAGDGPKPA ELPPTPGTER NPEMELEKVR MEFELTRLKY LHEKNQRQRQ HEVVMEQLQR ERQHEVVMEQ LQQEAAPRLF SGGLQNFLLP QNQFAMFLYC FIFIHIIYVT KEMVFFLFAK HYLFCIAAIL LCLIKTFWS
Explore Transmembrane protein 247 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets