About Uncharacterized protein C5orf52
Uncharacterized protein C5orf52 (C5orf52) is a protein
from Homo sapiens identified by UniProt accession
A6NGY3, 159 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Uncharacterized protein C5orf52 |
|---|
| UniProt accession | A6NGY3 |
|---|
| Gene | C5orf52 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.22
- neurofibrillary tangles measurement · score 0.21
- protein measurement · score 0.18
- FEV/FVC ratio · score 0.05
- mean corpuscular hemoglobin concentration · score 0.05
- systolic blood pressure · score 0.04
- diastolic blood pressure · score 0.04
- hair shape measurement · score 0.04
- brain volume measurement · score 0.04
- cardiovascular disease · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NGY3-F1 | alphafold | PREDICTED | 73.45 | — |
Amino-acid sequence (159 residues)
MTQPTRPSVT CDQGSSTIGG TAAQATTSSS ATSGSNYQRD RLGRRPEIGV GGQPQICFPR PRSAQQPVLF SLMNSSEAAM KKTLPKSHLS RVIIHDNRIT QRIYEMEVSA LEKTKKKISH YYEHLKKKFM TEQLRKLGRW REESVNSNRY LTFGIPPPV
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