Olfactory receptor 4C46 (OR4C46)

About Olfactory receptor 4C46

Olfactory receptor 4C46 (OR4C46) is a protein from Homo sapiens identified by UniProt accession A6NHA9, 309 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein name	Olfactory receptor 4C46
UniProt accession	A6NHA9
Gene	OR4C46
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (52)

Diseases linked to this target (Open Targets).

diastolic blood pressure · score 0.25
creatinine measurement · score 0.23
systolic blood pressure · score 0.21
prostate adenocarcinoma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
glomerular filtration rate · score 0.17
aspartate aminotransferase measurement · score 0.16
red blood cell density measurement · score 0.16
erythrocyte count · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NHA9-F1	alphafold	PREDICTED	88.45	—

Amino-acid sequence (309 residues)

MENRNNMTEF VLLGLTENPK MQKIIFVVFF VIYIITVVGY VLIVVTITAS PSLGSPMYLS LAYLSFIDAC YSSVNTPNLI THSLYGKKAI LFNGCMTQVF GEHFFGGAEG ILLTVMAYDH YVAICKPLHY MTIMNQCVCA LLMGVVWMGG FLHATIQILF IFQLPFCGPN VIDHFMCDLN PLLNLACTDT HMLELFIAAN SGFICLLNFA LLLVSYVVIL CSLRTHSLEA RHKALSTCVS HITVVILFFV PCIFVYMRPA ATLPIDKAVA IFYTMITPML NPLIYTLKNA QMKNAIRKLC SRKDISGDK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards