About Olfactory receptor 5B21
Olfactory receptor 5B21 (OR5B21) is a protein
from Homo sapiens identified by UniProt accession
A6NL26, 309 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 5B21 |
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| UniProt accession | A6NL26 |
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| Gene | OR5B21 |
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| Organism | Homo sapiens |
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| Length | 309 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- chronic lymphocytic leukemia · score 0.18
- ovarian cancer · score 0.18
- high density lipoprotein cholesterol measurement · score 0.11
- mean platelet volume · score 0.03
- mathematical ability · score 0.02
- monocyte count · score 0.02
- neoplasm · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NL26-F1 | alphafold | PREDICTED | 88.93 | — |
Amino-acid sequence (309 residues)
MENSTEVTEF ILLGLTDDPN LQIPLLLAFL FIYLITLLGN GGMMVIIHSD SHLHTPMYFF LSNLSLVDLG YSSAVAPKTV AALRSGDKAI SYDGCAAQFF FFVGFATVEC YLLASMAYDR HAAVCRPLHY TTTMTAGVCA LLATGSYVSG FLNASIHAAG TFRLSFCGSN EINHFFCDIP PLLALSCSDT RISKLVVFVA GFNVFFTLLV ILISYFFICI TIQRMHSAEG QKKVFSTCAS HLTALSIFYG TIIFMYLQPN SSQSVDTDKI ASVFYTVVIP MLNPLIYSLR NKEVKSALWK ILNKLYPQY
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