Retrotransposon Gag-like protein 8C (RTL8C)

About Retrotransposon Gag-like protein 8C

Retrotransposon Gag-like protein 8C (RTL8C) is a protein from Homo sapiens identified by UniProt accession A6ZKI3, 113 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Retrotransposon Gag-like protein 8C
UniProt accession	A6ZKI3
Gene	RTL8C
Organism	Homo sapiens
Length	113 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

ulcerative colitis · score 0.01
breast cancer · score 0.01
Alzheimer disease · score 0.01
colorectal cancer · score 0.01
myocarditis · score 0.00
diabetic nephropathy · score 0.00
acute myeloid leukemia · score 0.00
cancer · score 0.00
Cowden syndrome 1 · score 0.00
juvenile dermatomyositis · score 0.00

3D Structure

Predicted structure for A6ZKI3 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (113 residues)

MDGRVQLIKA LLALPIRPAT RRWRNPIPFP ETFDGDTDRL PEFIVQTGSY MFVDENTFSS DALKVTFLIT RLTGPALQWV IPYIKKESPL LNDYRGFLAE MKRVFGWEED EDF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards