About Zinc finger protein 850
Zinc finger protein 850 (ZNF850) is a protein
from Homo sapiens identified by UniProt accession
A8MQ14, 1090 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Zinc finger protein 850 |
|---|
| UniProt accession | A8MQ14 |
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| Gene | ZNF850 |
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| Organism | Homo sapiens |
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| Length | 1090 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.28
- neurodegenerative disease · score 0.23
- genetic disorder · score 0.12
- platelet count · score 0.03
- atypical teratoid rhabdoid tumor · score 0.03
- sex hormone-binding globulin measurement · score 0.02
- diet measurement · score 0.02
- Down syndrome · score 0.02
- hematocrit · score 0.02
- medulloblastoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MQ14-F1 | alphafold | PREDICTED | 72.15 | — |
Amino-acid sequence (1090 residues)
MNMEGLVMFQ DLSIDFSQEE WECLDAAQKD LYRDVMMENY SSLVSLGLSI PKPDVISLLE QGKEPWMVSR DVLGGWCRDS EFRCKTKDSC LPKEIYEVTS SQWVRMEKCH SLVGSSVRDD WECKGQFQHQ DINQERYLEK AIMTYETTPT FCLQTSLTLH HRIHPGEKLY KSTECMAFKY GSELTQQQET HTGEKLYKCK ECGKAFHHFS YLVKHQRIHT GEKPCACKEY GKAFISGSHL IQHQKMYTDE RPHECQESVK AFRPSAHLIQ HWRIHTGDKP YECKECGKSF TSGSTLNQHQ QIHTGEKPYH CKQCGKSFTV GSTLIRHQQI HTGEKPYDCK ECGKSFASGS ALIRHQRIHT GEKPYDCKEC GKSFTFHSAL IRHQRIHTGE KPYDCKECGK SFTFRSGLIG HQAIHTGEKP YDCKECGKSF TAGSTLIQHQ RIHTGEKPYD CKECGKSFAS GSALLQHQRI HTGEKPYCCK ECGKSFTFRS TRNRHQRIHT GEKPYNCKEC GKSFASGSAL LQHQRIHTGE KPYHCKECGK SFTFRSGLIG HQAVHTGEKP YDCKECGKSF TSRSALIQHQ RIHTGEKPYH CKECGKSFTV GSTLLQHQQI HTGEKPYDCK ECGKAFRLRL RLTQHQQIHT GEKPYQCQEC GKAFVSVSGL TQHHRIHTGE KPYECPDCGK AFRQRTYLNQ HRRIHTGEKP YECKECGKSF TFCSGLIQHQ QNHTDEKPYD GKECGKSFTS HSTLIQHQQI HTGEKPYDCK ECGKSFTSHS TLIQHQQIHT GEKLYDCKEC GKSFTSHSTL IQHQPLHTGE KPYHCKECGK SFTLRSALIQ HRPVHTGEKR YSCKECGKSF TSRSTLIEHQ RIHTGEKPYH CKECGKSFAF RSAIIQHRRI HTGEKPYDCK ECGKAFRRRS KLTQHQRIHT GEKPYRCHEC GKAFVRFSGL TKHHSIHTGE KPYECKTCGK SFRQRTHLTL HQRIHTGDRP YECKECGKSF TCGSELIRHQ RTHTGEKPYD CKECGKAFRC PSQLSQHKRI HTGEKTYQCP ECGKAFFYAS GLSRHQSVHT GEKPYECKTC GKAFKQLTQL TRHQRIHDLT
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