About Zinc finger B-box domain-containing protein 1
Zinc finger B-box domain-containing protein 1 (ZBBX) is a protein
from Homo sapiens identified by UniProt accession
A8MT70, 800 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Zinc finger B-box domain-containing protein 1 |
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| UniProt accession | A8MT70 |
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| Gene | ZBBX |
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| Organism | Homo sapiens |
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| Length | 800 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (23)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.30
- DNA methylation · score 0.21
- worry measurement · score 0.20
- breast milk measurement · score 0.19
- electroencephalogram measurement · score 0.17
- diet measurement · score 0.06
- venous thromboembolism · score 0.04
- electrocardiography · score 0.02
- ependymoma · score 0.01
- nasopharyngeal neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MT70-F1 | alphafold | PREDICTED | 50.24 | — |
Amino-acid sequence (800 residues)
MNRKDFVVLP WGKPGNSVKL KYRNAQELRM EKVQLEFENQ EMEKKLQEFR STRNKEKEDR ESSEYYWKSG KVGKLVNQSY MMSQNKGNVV KFSAGKVKLK LLKEQIQEPV KPTVNYKMAN SSECEKPKIN GKVCGQCENK AALLVCLECG EDYCSGCFAK VHQKGALKLH RTTLLQAKSQ ILFNVLDVAH QFIKDVNPDE PKEENNSTKE TSKIQHKPKS VLLQRSSSEV EITTMKRAQR TKPRKSLLCE GSFDEEASAQ SFQEVLSQWR TGNHDDNKKQ NLHAAVKDSL EECEVQTNLK IWREPLNIEL KEDILSYMEK LWLKKHRRTP QEQLFKMLPD TFPHPHETTG DAQCSQNEND EDSDGEETKV QHTALLLPVE TLNIERPEPS LKIVELDDTY EEEFEEAENI VPYKVKLADA DSQRSCAFHD CQKNSFPYEN GIHQHHVFDK GKRDFLNLCL RNSSTYYKDN SKAETSNTDF DNIVDPDVYS SDIEKIEEST SFERNLKEKN IGLESNQKSD DSCVSLESKD TLLGRDLEKA PIEEKLSQDI KESLELSNLY KRPSFEESKT TKSSLLLQEI ACRSKPITKQ YQGLERFFIF DTNERLNLLP SHRLECNNSS TRITLAGQKS QRPSTANFPL SNSVKESSSC LSSSHPRSRS AAAQSSSRAA SEISEIEYID ITDQNELSLD DTTDQHTLDN LEKELQVLRS LADTSEKLYS LTSEEFPDFS SQSLNISQIS TDFLKTSHVR GPCGVEELSC SGRDTKIQSL LSLSESSTDE EEEDFLNKQH VITLPWSKST
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