Serpin-like protein HMSD (HMSD)

About Serpin-like protein HMSD

Serpin-like protein HMSD (HMSD) is a protein from Homo sapiens identified by UniProt accession A8MTL9, 139 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Serpin-like protein HMSD
UniProt accession	A8MTL9
Gene	HMSD
Organism	Homo sapiens
Length	139 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.18
neurodegenerative disease · score 0.17
atopic eczema · score 0.16
cigarettes per day measurement · score 0.04
juvenile idiopathic arthritis · score 0.01
Yersinia pestis infectious disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MTL9-F1	alphafold	PREDICTED	80.08	—

Amino-acid sequence (139 residues)

MSISSALAMV FMGAKGNTAA QMSQALCFSK IGGEDGDIHR GFQSLLVAIN RTDTEYVLRT ANGLFGEKSY DFLTGFTDSC GKFYQATIKQ LDFVNDTEKS TTRVNSWVAD KTKGENILLF YFDNILNSFI VSSLQNCQI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards