About Galectin-16
Galectin-16 (LGALS16) is a protein
from Homo sapiens identified by UniProt accession
A8MUM7, 142 residues long.
MolForge cross-references it against 0 known binders and
125 disease associations.
Target properties
| Protein name | Galectin-16 |
|---|
| UniProt accession | A8MUM7 |
|---|
| Gene | LGALS16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 142 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (125)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- Familial hemophagocytic lymphohistiocytosis · score 0.05
- Felty's syndrome · score 0.05
- immunodeficiency 72 with autoinflammation · score 0.05
- hyper-IgM syndrome type 3 · score 0.05
- osteoarthritis · score 0.05
- immunodeficiency 99 with hypogammaglobulinemia and autoimmune cytopenias · score 0.05
- glycoprotein storage disease · score 0.05
- common variable immunodeficiency · score 0.05
- combined immunodeficiency due to partial RAG1 deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MUM7-F1 | alphafold | PREDICTED | 94.61 | — |
Amino-acid sequence (142 residues)
MSFLTVPYKL PVSLSVGSCV IIKGTLIDSS INEPQLQVDF YTEMNEDSEI AFHLRVHLGR RVVMNSREFG IWMLEENLHY VPFEDGKPFD LRIYVCHNEY EVKVNGEYIY AFVHRIPPSY VKMIQVWRDV SLDSVLVNNG RR
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