HIG1 domain family member 1C (HIGD1C)

About HIG1 domain family member 1C

HIG1 domain family member 1C (HIGD1C) is a protein from Homo sapiens identified by UniProt accession A8MV81, 97 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	HIG1 domain family member 1C
UniProt accession	A8MV81
Gene	HIGD1C
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

unipolar depression · score 0.29
vitamin D measurement · score 0.29
mean corpuscular hemoglobin concentration · score 0.05
mean corpuscular hemoglobin · score 0.02
chronic kidney disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A8MV81-F1	alphafold	PREDICTED	64.68	—

Amino-acid sequence (97 residues)

MSSDNQWSAD EDEGQLSRLI RKSRDSPFVP IGIAGFVTVV SCGLYKLKYR RDQKMSIHLI HMRVAAQGFV VGAVTLGVLY SMYKDYIRPR FFSESKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards