About Protein HIDE1
Protein HIDE1 (HIDE1) is a protein
from Homo sapiens identified by UniProt accession
A8MVS5, 230 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Protein HIDE1 |
|---|
| UniProt accession | A8MVS5 |
|---|
| Gene | HIDE1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 230 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.11
- BMI-adjusted waist-hip ratio · score 0.08
- hyperlipidemia · score 0.07
- age at diagnosis · score 0.07
- eosinophil count · score 0.06
- Ischemic stroke · score 0.06
- mean corpuscular volume · score 0.06
- hypertrophic cardiomyopathy · score 0.06
- body height · score 0.06
- Arrhythmogenic right ventricular dysplasia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MVS5-F1 | alphafold | PREDICTED | 73.86 | — |
Amino-acid sequence (230 residues)
MPWTILLFAA GSLAIPAPSI RLVPPYPSSQ EDPIHIACMA PGNFPGANFT LYRGGQVVQL LQAPTDQRGV TFNLSGGSSK APGGPFHCQY GVLGELNQSQ LSDLSEPVNV SFPVPTWILV LSLSLAGALF LLAGLVAVAL VVRKVKLRNL QKKRDRESCW AQINFDSTDM SFDNSLFTVS AKTMPEEDPA TLDDHSGTTA TPSNSRTRKR PTSTSSSPET PEFSTFRACQ
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