About PHD finger protein 20-like protein 1
PHD finger protein 20-like protein 1 (PHF20L1) is a protein
from Homo sapiens identified by UniProt accession
A8MW92, 1017 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | PHD finger protein 20-like protein 1 |
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| UniProt accession | A8MW92 |
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| Gene | PHF20L1 |
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| Organism | Homo sapiens |
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| Length | 1017 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (42)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.23
- body fat percentage · score 0.18
- mean reticulocyte volume · score 0.16
- red blood cell density measurement · score 0.15
- erythrocyte count · score 0.13
- substance abuse · score 0.10
- attention deficit hyperactivity disorder · score 0.10
- antisocial behaviour measurement · score 0.10
- platelet component distribution width · score 0.09
- breast cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A8MW92-F1 | alphafold | PREDICTED | 53.97 | — |
Amino-acid sequence (1017 residues)
MSKKPPNRPG ITFEIGARLE ALDYLQKWYP SRIEKIDYEE GKMLVHFERW SHRYDEWIYW DSNRLRPLER PALRKEGLKD EEDFFDFKAG EEVLARWTDC RYYPAKIEAI NKEGTFTVQF YDGVIRCLKR MHIKAMPEDA KGQVKSQHPL SWCCPIDPAG SCNQSMGSED WIALVKAAAA AAAKNKTGSK PRTSANSNKD KDKDERKWFK VPSKKEETST CIATPDVEKK EDLPTSSETF GLHVENVPKM VFPQPESTLS NKRKNNQGNS FQAKRARLNK ITGLLASKAV GVDGAEKKED YNETAPMLEQ AISPKPQSQK KNEADISSSA NTQKPALLSS TLSSGKARSK KCKHESGDSS GCIKPPKSPL SPELIQVEDL TLVSQLSSSV INKTSPPQPV NPPRPFKHSE RRRRSQRLAT LPMPDDSVEK VSSPSPATDG KVFSISSQNQ QESSVPEVPD VAHLPLEKLG PCLPLDLSRG SEVTAPVASD SSYRNECPRA EKEDTQMLPN PSSKAIADGR GAPAAAGISK TEKKVKLEDK SSTAFGKRKE KDKERREKRD KDHYRPKQKK KKKKKKKSKQ HDYSDYEDSS LEFLERCSSP LTRSSGSSLA SRSMFTEKTT TYQYPRAILS VDLSGENLSD VDFLDDSSTE SLLLSGDEYN QDFDSTNFEE SQDEDDALNE IVRCICEMDE ENGFMIQCEE CLCWQHSVCM GLLEESIPEQ YICYICRDPP GQRWSAKYRY DKEWLNNGRM CGLSFFKENY SHLNAKKIVS THHLLADVYG VTEVLHGLQL KIGILKNKHH PDLHLWACSG KRKDQDQIIA GVEKKIAQDT VNREEKKYVQ NHKEPPRLPL KMEGTYITSE HSYQKPQSFG QDCKSLADPG SSDDDDVSSL EEEQEFHMRS KNSLQYSAKE HGMPEKNPAE GNTVFVYNDK KGTEDPGDSH LQWQLNLLTH IENVQNEVTS RMDLIEKEVD VLESWLDFTG ELEPPDPLAR LPQLKRHIKQ LLIDMGKVQQ IATLCSV
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