About Serine/arginine repetitive matrix protein 5
Serine/arginine repetitive matrix protein 5 (SRRM5) is a protein
from Homo sapiens identified by UniProt accession
B3KS81, 715 residues long.
MolForge cross-references it against 0 known binders and
4 disease associations.
Target properties
| Protein name | Serine/arginine repetitive matrix protein 5 |
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| UniProt accession | B3KS81 |
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| Gene | SRRM5 |
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| Organism | Homo sapiens |
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| Length | 715 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (4)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- appendicular lean mass · score 0.10
- forced expiratory volume · score 0.07
- myelodysplastic syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B3KS81-F1 | alphafold | PREDICTED | 41.81 | — |
Amino-acid sequence (715 residues)
MSSPKRSSKP SMSLAPSGSS MPTADPKPPA SLKSTKSATP NRSLVPTKPA TSRNSVMSPS SSKSTKSTST KRAPSNRPSS RSRVRSKART PSRVSTDTRT SKASKASDVR CHQRRGTHSR GRTPGRRGSR SSKRSPSRAS TPGRIRTHGA RPGMASRVRT PTSQQKGSRG KSYGRPRTSN RERSDSQPRN LSKKSYRPPG GSGIGRSSEL AVTPSTAKCQ TPTGIPSKEK SDNPSPSSSR KVKSYGQMII PSREKSYSPT EMSSRVKSYN QASTRSRPQS HSQSRSPRRS RSGSQKRTHS RVRSHSWKRN HSRARSRTRK GILSQMGRHS QSRSHSKGKS QNQSRTPRRG RSHNWSRNPS KERSHSHSRS SSKERDHRGS SSPRKESGRS QSGSPNKQRD HSRSRSPNKA RDRSRSRSPY KARDRSRSRS PNKARDCSRS RSPYKARDRS RSRSPNKARD HSRSRSPNKA RDRSRSRSPS KERDHSQLGS PSKERDHRRS RSPSKERQCR QSRSSSKERD HRRSRSPSKE RQRRQSRSPN KERDRSQSRS PSEEREHRQS RSPSKERDRR RWRSPSKERE RRQSRSSSEE RDHSRSRSPN KQSGYSRPRA SSKEKAHSRS RTPSKEGNHS QSRTSSKESD PSQSTVPRSP DWKRSPTRTS SLSQNRTPSK TSSHSPSTFP SGGQTLSQDD SQADATTSKA TLPGERSSSS SSKLA
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