Transmembrane protein 233 (TMEM233)

About Transmembrane protein 233

Transmembrane protein 233 (TMEM233) is a protein from Homo sapiens identified by UniProt accession B4DJY2, 109 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Transmembrane protein 233
UniProt accession	B4DJY2
Gene	TMEM233
Organism	Homo sapiens
Length	109 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

monocyte count · score 0.40
adverse effect · score 0.31
low density lipoprotein cholesterol measurement · score 0.26
basophil count · score 0.15
metabolite measurement · score 0.06
leukocyte count · score 0.05
basophil percentage of leukocytes · score 0.05
lymphocyte percentage of leukocytes · score 0.05
risky sexual behaviour measurement · score 0.04
myeloid white cell count · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B4DJY2-F1	alphafold	PREDICTED	60.27	—

Amino-acid sequence (109 residues)

MSQYAPSPDF KRALDSSPEA NTEDDKTEED VPMPKNYLWL TIVSCFCPAY PINIVALVFS IMSLNSYNDG DYEGARRLGR NAKWVAIASI IIGLLIIGIS CAVHFTRNA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards